Publications by authors named "F St Michael"
Background: There is consensus on the safety of standard dose direct oral anticoagulants (DOACs) for stroke prevention in patients undergoing cardioversion of atrial fibrillation (AF), but outcomes of reduced dose DOACs in this setting remain unclear.
Objective: This systematic review and meta-analysis aimed to compare the rate of cardioversion-associated thromboembolic events between patients taking reduced dose DOACs and those receiving standard dose anticoagulation.
Methods: A systematic search was conducted for studies published between January 1, 2009, and February 16, 2024 in PubMed, Embase, and Cochrane Central Register of Controlled Trials.
Risk of bleeding with the concurrent use of amiodarone and DOACs: A systematic review and meta-analysis.
Eur Heart J Cardiovasc Pharmacother
December 2024
Background And Aims: Amiodarone is frequently prescribed alongside direct oral anticoagulants (DOACs) in atrial fibrillation (AF). There are concerns regarding drug-drug interactions (DDIs) between amiodarone and DOACs. The literature is conflicting on the clinical implications of this DDI, hence we conducted a meta-analysis to compare bleeding risk among patients receiving DOACs, with and without concurrent amiodarone.
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- The study aimed to investigate how alcohol consumption is linked to stroke occurrences in Nigeria and Ghana by comparing individuals who had strokes to those who didn't.!
- It involved over 7,368 participants, classifying them into groups based on their alcohol consumption habits, and utilized various statistical models to analyze the data.!
- Results indicated that current drinkers had a higher risk of stroke, particularly among moderate, binge, and heavy drinkers, while former drinkers showed no significant stroke risk. !
Background: Rotavirus vaccines are moderately protective against illness in high mortality settings compared with low mortality settings. Vaccine effectiveness (VE) evaluations may clarify our understanding of these disparities, but estimates among key subpopulations and against rare outcomes are not available in many analyses due to sample size. We combined 25 datasets from test-negative design case-control evaluations in 24 countries that enrolled children with medically-attended diarrhea, laboratory-confirmed rotavirus stool testing, and documented vaccination status.
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- Language barriers in healthcare can lead to serious issues like misdiagnosis and high medical errors, highlighting the need for effective translation methods that go beyond traditional interpreters.
- * This pilot study evaluates Translatly, a digital translation platform, to see how well it can help healthcare professionals communicate during consultations, particularly assessing its usability and acceptance in clinical settings.
- * The study involved interviews and observations in a German hospital, focusing on how the platform functions with volunteer translators, primarily medical students, offering support in multiple languages.