Frailty and social network among older Brazilian adults: evidence from ELSI-Brazil.

To investigate the elements of the social network associated with frailty syndrome in older Brazilian adults. Baseline data from the Brazilian Longitudinal Study of Aging (ELSI-Brazil, 2015-2016) were used. Frailty was defined by the Fried phenotype (unintentional weight loss, exhaustion, weakness, slowness, and low level of physical activity).

Psychometric analysis of ProQOL-BR in nursing: building hospital safety and protection.

Objectives: to analyze the psychometric properties of the ProQOL-BR instrument in hospital nursing professionals.

Methods: a methodological study to validate the ProQOL-BR. Confirmatory factor analysis, assessment of local and global adjustment quality, Pearson hypothesis testing and Cronbach's alpha internal consistency analysis were used.

Hydrogel-antimicrobial peptide association: A novel and promising strategy to combat resistant infections.

Infections from multi-drug resistant bacteria (MDRB) have raised a worldwide concern, with projections indicating that fatalities from these infections could surpass those from cancer by 2050. This troubling trend is influenced by several factors, including the scarcity of new antibiotics to tackle challenging infections, the prohibitive costs of last-resort antibiotics, the inappropriate use of antimicrobial agents in agriculture and aquaculture, and the over-prescription of antibiotics in community settings. One promising alternative treatment is the application of antimicrobial peptides (AMPs) against MDRB.

Influence of agarose in semi-IPN hydrogels for sustained Polymyxin B release.

Hydrogels (HGs) are 3-D polymeric networks with high water content, making them appropriate for biomedical applications such as drug delivery systems. This study examines the impact of agarose in semi-interpenetrating polymer networks (Semi-IPNs) based on poly(acrylic acid) (p(AA)), N, N' Methylenebis(acrylamide) (MBA) and agarose (AGA) on the sustained release of Polymyxin B (PolB). Agarose incorporation improved the mechanical strength, swelling behavior and drug retention capacity of the HG.

Ultrasonographic findings in female inmates in a prison unit in the state of São Paulo, Brazil.

Objective: To characterize the ultrasonographic findings in female inmates in a prison unit in the state of São Paulo, Brazil, and to analyze the associations between ultrasonographic findings and sociodemographic characteristics.

Materials And Methods: This was a retrospective cohort study that analyzed the ultrasonographic examinations performed in consecutive female inmates in a prison unit in the city of São Paulo, between 2015 and 2020. The following ultrasound examinations were performed: soft tissue, thyroid, cervical, breast, transvaginal, pelvic gynecology, total abdomen, upper abdomen, and kidney/urinary tract in B-mode, with color Doppler, or both.