Relationship between Helicobacter pylori infection and gastric follicular hyperplasia. A retrospective study.

Background: The occurrence of lymphoid follicles in the gastric mucosa was recently considered to be acquired in respose to infection by Helicobacter pylori.

Methods: In order to investigate whether there is any correlation between follicular hyperplasia and Helicobacter pylori colonization, a morphological study was performed in antral biopsy specimens from 267 patients with H. pylori-associated gastritis, and from 312 subjects with histological evidence of chronic gastritis, but without H.

A retrospective study on the incidence of lymphocytic gastritis in patients with Helicobacter pylori infection.

To investigate the relationship between lymphocytic gastritis and H. pylori infection, antral biopsy specimens from 162 patients with histological evidence of H. pylori infection, and from 177 subjects without colonization were retrospectively examined.

Helicobacter pylori in Barrett's esophagus and in normal or inflamed esophageal mucosa: a retrospective study.

To investigate on the presence and significance of Helicobacter pylori (Hp) in Barrett's mucosa, esophageal biopsy specimens from 34 patients with columnar-lined epithelium were retrospectively examined. The incidence of colonization was compared with that observed in a control group of 76 subjects with normal esophageal mucosa or moderate esophagitis. Three of the 34 Barrett's specimens were Hp-positive and only 1 of these showed evidence of inflamed mucosa (p = NS).

Effect of Helicobacter pylori colonization on quantitative distribution of antral G-cells in apparently healthy subjects and in duodenal ulcer patients. A morphometric study.

To investigate whether antral colonization by Helicobacter pylori (Hp) modifies gastrin-cell population, the number of G-cells was evaluated in antral biopsy specimens from 22 apparently healthy subjects and from 48 duodenal ulcer patients using a morphometric method. The level of serum immunoreactive gastrin in a sample of fasting serum obtained at the time of biopsy was also measured. In healthy subjects the G-cell count (evaluated according to G/I index) and the serum gastrin levels were not significantly different than those found in duodenal ulcer patients.

[The relationship between dietary intake of vitamin A and risk of gastrointestinal neoplasia].

A study on dietary intake of retinol and beta-carotene was conducted in 51 patients affected by gastric (23 cases) and colorectal (28 cases) carcinoma, considering the period preceding the onset of their illness. In all patients were measured serum retinol levels. The data were compared with those in 44 control subjects.