Publications by authors named "F Shimamoto"

Background: Additional surgery with lymph node (LN) dissection is recommended for pT1 colorectal carcinoma (CRC) resected by endoscopy, based on pathological risk factors for LN metastasis (LNM), according to guidelines by the Japanese Society for Cancer of the Colon and Rectum (JSCCR), National Comprehensive Cancer Network (NCCN), and European Society for Medical Oncology (ESMO).

Methods: We retrospectively analyzed 560 consecutive patients with T1 CRC who underwent endoscopic resection alone (n=190) or initial or additional surgery with LN dissection (n=370) between 1992 and 2017 at Hiroshima University Hospital. Patients were classified into LNM low- and high-risk groups according to guidelines by the JSCCR, NCCN, and ESMO as follows.

View Article and Find Full Text PDF

Background/objectives: Colorectal neoplasia developing from ulcerative colitis mucosa (CRNUC) can be divided into ulcerative colitis-associated neoplasia (UCAN) and non-UCAN; however, it is often difficult to distinguish UCAN from non-UCAN during a biopsy diagnosis. We investigated whether a genomic analysis could improve the diagnostic accuracy of UCAN using biopsy specimens.

Methods: In step 1, 14 CRNUCs were used to examine whether the genomic landscape of biopsy and resection specimens matched.

View Article and Find Full Text PDF

Unlabelled: PURPOSE : A vertical margin (VM) distance of < 500 µm is a risk factor for recurrence in patients with T1 colorectal carcinoma (CRC) resected by endoscopy. We aimed to determine the effects of the VM distance on the recurrence and prognosis of T1 CRC.

Methods: We enrolled 168 patients with T1 CRC who underwent additional surgery after endoscopic submucosal dissection (ESD) at multiple centers between 2008 and 2016.

View Article and Find Full Text PDF
Article Synopsis
  • Benign lymphoid polyps of the rectum, also known as "Rectal tonsil" or "Pseudolymphoma," are benign growths that can be mistaken for other tumors due to similar appearance during colonoscopy.
  • A 72-year-old woman with a positive fecal occult blood test had a 10-mm rectal tumor resembling a neuroendocrine tumor, which was successfully removed via endoscopic submucosal resection with a ligation device (ESMR-L).
  • Histopathological analysis confirmed the benign nature of the lesion, highlighting the challenges in differentiating it from more serious conditions like carcinoid tumors and malignant lymphomas.
View Article and Find Full Text PDF

Introduction: Patients with ulcerative colitis (UC) develop not only UC-associated neoplasias but also sporadic neoplasias (SNs). However, few studies have described the characteristics of SNs in patients with UC. Therefore, this study aimed to evaluate the clinical features and prognosis of SNs in patients with UC.

View Article and Find Full Text PDF