Klebsiella pneumoniae employs a type VI secretion system to overcome microbiota-mediated colonization resistance.

Microbial species must compete for space and nutrients to persist in the gastrointestinal (GI) tract, and our understanding of the complex pathobiont-microbiota interactions is far from complete. Klebsiella pneumoniae, a problematic, often drug-resistant nosocomial pathogen, can colonize the GI tract asymptomatically, serving as an infection reservoir. To provide insight on how K.

Meta-analysis of longitudinal comparison of transcatheter versus surgical aortic valve replacement in patients at low to intermediate surgical risk.

Background: Surgical aortic valve replacement (SAVR) is the commonly used approach for aortic valve replacement (AVR) in patients with aortic stenosis at low or intermediate surgical risk. However, transcatheter aortic valve replacement (TAVR) has emerged as an alternative to SAVR for AVR. This meta-analysis aims to assess the comparative efficacy and safety of TAVR versus SAVR in low-to-intermediate surgical risk patients by analyzing temporal trends in the outcomes of TAVR and SAVR at various follow-up intervals, providing a more detailed understanding.

When surgery leaves more than just scars: The curious case of gossypiboma- A case report and literature review.

Gossypiboma is a unique postoperative complication characterized by the presence of a surgical sponge after surgery. This condition is seldom encountered. Owing to its serious medicolegal implications it remains underreported leading to a blurred clinical spectrum.

Rising cardiovascular mortality among obstructive sleep apnea patients: United States epidemiological trends (1999-2019).

Background: Obstructive sleep apnea (OSA) prevalence has risen significantly, affecting millions globally and posing a major healthcare burden. OSA is strongly associated with cardiovascular diseases (CVD) such as heart failure, stroke, and ischemic heart disease. However, trends in CVD-related mortality among individuals with OSA remain underexplored.

Bridging the Gap: Promoting Interventional Pain Medicine as a Future for Family Physicians.

The use of interventional pain medicine (IPM) has been growing over the past few years, offering relief to patients suffering from acute and chronic pain who have failed conservative therapies. Pain is one of the top complaints that family physicians encounter, yet there is no official pain medicine (PM) fellowship or recognized training program that favors family medicine graduates. Although family medicine residency programs allot a certain amount of time to teaching trainees in PM, this is considerably insufficient and does not dedicate ample time for procedural treatments.