Publications by authors named "F Severac"

Introduction: Transthyretin cardiac amyloidosis is a pathology increasingly encountered in all hospital departments, including internal medicine. The aim of our study is to describe the characteristics and care pathway of patients with transthyretin cardiac amyloidosis in internal medicine and to show that the number of patients diagnosed is increasing.

Methods: Descriptive, retrospective, non-interventional, single-center study at Strasbourg University Hospitals (HUS).

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Background: Glanzmann thrombasthenia (GT) is a very rare autosomal inherited bleeding disease affecting megakaryocyte lineage with impacts on oral health such as gingival bleeding, which requires specific management protocols. Very few clinical cases have been published in the dental and hematologic literature.

Objectives: This study focuses on a series of 21 patients affected specifically by GT and their hemorrhagic prophylaxis management with the use of recombinant activated factor VII (rFVIIa) for dental extractions and full-mouth debridement.

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Article Synopsis
  • The study aims to determine how rod characteristics, screw density, and cages affect mechanical complications in spinal surgeries compared to patient-related factors and alignment in adult spinal deformity cases.
  • Data from 302 patients was analyzed using different statistical models to measure outcomes like pseudarthrosis and screw loosening and understand the impact of surgical techniques versus patient demographics.
  • Key findings include that using four rods reduces the risk of pseudarthrosis, postoperative malalignment significantly increases the risk of complications, and high screw density leads to a lower risk of screw loosening, while age has a secondary impact on outcomes.
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  • - Patients with tachycardia-induced cardiomyopathy (TIC) show better left atrial (LA) health, evidenced by lower LA volume, higher voltage, and fewer low-voltage zones (LVZs) compared to those without TIC.
  • - In a study of 139 persistent atrial fibrillation patients undergoing catheter ablation, those with TIC had less atrial remodeling and a 36-month follow-up showed no significant difference in the rate of atrial tachyarrhythmia (AT) recurrence between TIC and non-TIC groups.
  • - Overall, the findings suggest TIC patients have similar, if not improved, outcomes following ablation procedures, despite possessing a less remodeled atrial substrate.
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