Publications by authors named "F Serraino"

Article Synopsis
  • Mechanical complications (MCs) following acute myocardial infarction (AMI) are rare but serious, with surgery being the recommended treatment; this study evaluated outcomes of patients who underwent such surgeries from 2001 to 2019.
  • Among 720 patients analyzed, the average age was 70, with the majority being male; the most frequent complication was ventricular septal rupture, leading to a significant in-hospital mortality rate of 37.4%.
  • Despite high immediate mortality, long-term survival rates for hospital survivors were promising, showing 65.7% survival at 10 years, with older age and postoperative low cardiac output syndrome being key factors influencing overall mortality.
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Objectives: Although the intra-aortic balloon pump (IABP) has been the most widely adopted temporary mechanical support device in cardiac surgical patients, its use has declined. The current study aimed to evaluate the occurrence and predictors of early mortality and complication rates in contemporary cardiac surgery patients supported by an IABP.

Methods: A multicentre, retrospective analysis was performed of all consecutive cardiac surgical patients receiving perioperative balloon pump support in 8 centres between January 2010 to December 2019.

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Cardiopulmonary bypass (CPB) may trigger organs damage, including kidney injury, due to a massive cytokine release. In this observational, prospective study, we analyzed the possible impact of chronic treatment with ACE-Inhibitors (ACE-I) on the inflammatory response and renal function after CPB. Sixty-nine patients undergoing major cardiac surgery with CPB were enrolled.

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Permanent pacemaker implantation (PPI) represents a rare complication after cardiac surgery, with no uniform agreement on timing and no information on follow-up. A multicenter retrospective study was designed to assess pacemaker dependency (PMD) and long-term mortality after cardiac surgery procedures. Between 2004 and 2016, PPI-patients from 18 centers were followed.

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Article Synopsis
  • This study analyzed the outcomes of patients who underwent mitral valve replacement (MVR) using a third-generation Mosaic porcine bioprosthesis across 11 cardiac centers from 1998 to 2011, involving 805 patients with an average age of 73.5 years.
  • The median follow-up duration was 44 months, revealing early mortality rates of 3.8% for isolated elective surgeries and 7.8% overall, with a 10-year survival rate of 57.4% and various other complication rates such as thromboembolic and hemorrhagic events.
  • The findings suggest that the Mosaic porcine bioprosthesis provides satisfactory early and long-term outcomes for patients undergoing MVR, with promising
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