Publications by authors named "F Sensi"
Article Synopsis
- Macrophages play a crucial role in the immune response within the tumor environment of colorectal cancer (CRC), and their unique properties can be harnessed to create targeted nanoparticles for treatment.
- Lipid nanovesicles (LNVs) were developed using membrane proteins from differentiated THP-1 cells, resulting in two types: T-LNVs and M1-LNVs, both loaded with the cancer drug doxorubicin (DOXO).
- M1-LNVs demonstrated greater effectiveness in targeting and killing cancer cells compared to T-LNVs, showing promise for precision medicine in cancer therapy with reduced side effects.
Background: Data on the predictors of percutaneous stellate ganglion block (PSGB) efficacy in electrical storm are scanty.
Objective: We aimed to assess whether PSGB efficacy is influenced by the arrhythmia type and cycle length before the procedure.
Methods: This is a subanalysis of the multicenter STAR study.
Efficacy of early use of percutaneous stellate ganglion block for electrical storms.
Eur Heart J Acute Cardiovasc Care
December 2024
Article Synopsis
- Electrical Storm (ES) is a critical condition that can be managed effectively using a technique called Percutaneous Stellate Ganglion Block (PSGB), which has shown positive results when used alongside standard therapy.
- In a study analyzing 180 patients, those who received PSGB early experienced a significant reduction in arrhythmic events within the hour following the block compared to the hour before, although the overall effectiveness was similar to those who received PSGB later.
- The findings suggest that early use of PSGB could help reduce the frequency of defibrillations and potentially lessen the risk of a more severe, refractory ES, demonstrating its effectiveness in early treatment settings.
Article Synopsis
- The study reviews 3.5 years of remote follow-up for cardiac implants during the COVID-19 pandemic to analyze its effectiveness and organization.
- A total of 1,937 patients participated, with 1,409 continuing under remote monitoring, showing high transmission success rates (96.6% for automatic vs. 87% for manual systems).
- Conventional in-hospital visits dropped by 44%, while clinic operational time reduced to 25% less than before, indicating a shift towards effective remote healthcare management.