Publications by authors named "F Scott Sicard"
Article Synopsis
- White adipose tissue (WAT) plays a crucial role in inflammation related to obesity and aging, as well as in the storage of vitamin D compounds.
- The study measured levels of cholecalciferol and 25-hydroxyvitamin D (25(OH)D) in mice, finding that aging and obesity lead to lower plasma levels of these vitamins without significantly altering circulating inflammatory markers.
- However, both aging and obesity increased inflammatory indicators in WAT, suggesting that the accumulation of vitamin D in this tissue may help mitigate inflammation linked to these conditions.
Article Synopsis
- Several studies suggest that lycopene and tomato products may enhance metabolic health, particularly in environments that promote obesity.
- The research involved 80 male mice fed different diets supplemented with tomato powders from various genotypes, exploring their effects on obesity-related health issues.
- Results showed that certain tomato genotypes improved fasting blood sugar and reduced liver fat, with one genotype (IL6-2) notably decreasing body weight and improving glucose levels, while irrigation levels had little effect on these health benefits.
Time around parturition is a stressful period for both bitches and their puppies. The use of probiotics has been proposed, e.g.
View Article and Find Full Text PDFAging and obesity are associated with a decrease in plasma 25-hydroxyvitamin D (25(OH)D) levels. In the context of a growing aging population and the rising incidence of obesity, we hypothesized that aging process, either independently or in combination with obesity, could influence vitamin D (VD) metabolism, consequently resulting in the reduced 25(OH)D plasma concentrations. C57BL/6JRJ young (6 months) and old (23 months) mice fed with control (CD) or high fat diet (HF) were compared.
View Article and Find Full Text PDFArticle Synopsis
- - This study investigates how vitamin D (VD) affects the lipid composition of extracellular vesicles derived from adipocytes (AdEVs), which can influence energy balance and inflammation.
- - Research using a specialized approach (LC-MS/MS) identifies differences in lipid types between small (sEVs) and large extracellular vesicles (lEVs), showing that VD alters lipid profiles, especially under inflammation.
- - The findings suggest that VD, both independently and during inflammatory responses, creates a distinct lipid signature in AdEVs, supporting its role in reducing inflammation.