Publications by authors named "F Sciancalepore"

Article Synopsis
  • The Italian Fund for Alzheimer's enabled a survey in 2020 to analyze cognitive disorder centers, focusing on their organization, administrative features, and professional profiles.
  • A recent survey showed a rise in using a Minimum Core Test (MCT) for neuropsychological assessments in these centers from 45.7% in 2015 to 57.1% in 2022, with regional differences noted.
  • The presence of psychologists and being a university-affiliated center significantly increased the likelihood of MCT use, indicating the need for improved diagnostic practices and addressing regional disparities.
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Objective: Reciprocal connections exist between mental health and physical health, and conditions of cellular senescence/advanced biological age have been observed in association with certain psychiatric diseases. However, the construct of frailty has only preliminarily been explored in young adults and in relation to psychopathology so far. In the present study we aimed at further elucidating the relationships linking psychopathological phenomena with physical diseases in a sample of young adults.

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Cognition-oriented treatments (COTs) are a group of non-pharmacological treatments aimed at maintaining or improving cognitive functioning. Specific recommendations on the use of these interventions in people living with dementia (PLwD) are included in the Italian Guideline on the Diagnosis and Treatment of Dementia and Mild Cognitive Impairment, developed by the Italian National Institute of Health. This systematic review and meta-analysis, based on the GRADE methodology, is part of the guideline.

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Article Synopsis
  • A systematic review was conducted to estimate the global prevalence, incidence, and mortality rates of myasthenia gravis (MG) and related syndromes, due to a gap in recent investigations.
  • The review analyzed 94 studies published from 1952 to 2022, finding a mean prevalence of 173.3 cases per million, a mean incidence of 15.7 cases per million person-years, and a mean mortality rate of 1.4 cases per million person-years, with acetylcholine receptor (AChR)-MG being the most common subtype.
  • The review highlighted that the significant increase in reported MG cases may stem from enhanced research methods and diagnostic tools, though variations in MG frequencies exist due to
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Purpose: Intra-articular injections of hyaluronic acid (HA) and platelet-rich plasma (PRP) represent promising options in the conservative treatment of early stages of knee osteoarthritis (OA). Although the combined use of these two compounds seems to have a synergistic effect in pre-clinical studies, few clinical trials compared the association of PRP and HA with PRP and HA alone. The aim of study is to evaluate the efficacy of combined intra-articular injections of PRP and HA in the treatment of mild to moderate knee OA, compared to PRP and HA alone.

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