Publications by authors named "F Schramel"
Introduction: Many COVID-19 survivors suffer from persisting sequelae after acute disease. This is referred to as long COVID. The objectives of this study were to assess factors associated with long COVID and to analyze differences in persistent symptoms, findings on chest imaging, and pulmonary function between intensive care unit (ICU) and non-ICU hospitalized patients.
View Article and Find Full Text PDFESPEN guidelines recommend a minimum protein intake of 1.0 g/kg body weight (BW) per day to maintain or restore lean body mass in patients with cancer. During anti-cancer treatment, optimal protein intake is difficult to achieve.
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- Recent advancements in molecular diagnostics and drug treatments have shifted lung cancer treatment from traditional platinum-based chemotherapy to more personalized approaches like targeted therapies and immunotherapies, though these options are expensive.
- Traditional evaluation methods for treatment cost-effectiveness rely on randomized control trials (RCTs), which often don't reflect the real-world patient population who typically have worse prognoses.
- This study developed a patient-level microsimulation model based on real-world data in the Netherlands to assess personalized treatment strategies for advanced non-squamous NSCLC, validating it by comparing simulated outcomes with actual patient survival rates.
Background: Many studies have compared real-world clinical outcomes of immunotherapy in patients with metastatic non-small cell lung cancer (NSCLC) with reported outcomes data from pivotal trials. However, any differences observed could be only limitedly explored further for causation because of the unavailability of individual patient data (IPD) from trial participants. The present study aims to explore the additional benefit of comparison with IPD.
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