CHCHD4 binding affects the active site of apoptosis inducing factor (AIF): Structural determinants for allosteric regulation.

Apoptosis-inducing factor (AIF), which is confined to mitochondria of normal healthy cells, is the first identified caspase-independent cell death effector. Moreover, AIF is required for the optimal functioning of the respiratory chain machinery. Recent findings have revealed that AIF fulfills its pro-survival function by interacting with CHCHD4, a soluble mitochondrial protein which promotes the entrance and the oxidative folding of different proteins in the inner membrane space.

uB-VisioGeoloc: An image sequences dataset of pedestrian navigation including geolocalised-inertial information and spatial sound rendering of the urban environment's obstacles.

The dataset proposed is a collection of pedestrian navigation data sequences combining visual and spatial information. The pedestrian navigation sequences are situations encountered by a pedestrian walking in an urban outdoor environment, such as moving on the sidewalk, navigating through a crowd, or crossing a street when the pedestrian light traffic is green. The acquired data are timestamped provided RGB-D images and are associated with GPS, and inertial data (acceleration, rotation).

Outdoor Navigation Assistive System Based on Robust and Real-Time Visual-Auditory Substitution Approach.

Blindness affects millions of people worldwide, leading to difficulties in daily travel and a loss of independence due to a lack of spatial information. This article proposes a new navigation aid to help people with severe blindness reach their destination. Blind people are guided by a short 3D spatialised sound that indicates the target point to follow.

Cross-modal correspondence enhances elevation localization in visual-to-auditory sensory substitution.

Introduction: Visual-to-auditory sensory substitution devices are assistive devices for the blind that convert visual images into auditory images (or soundscapes) by mapping visual features with acoustic cues. To convey spatial information with sounds, several sensory substitution devices use a Virtual Acoustic Space (VAS) using Head Related Transfer Functions (HRTFs) to synthesize natural acoustic cues used for sound localization. However, the perception of the elevation is known to be inaccurate with generic spatialization since it is based on notches in the audio spectrum that are specific to each individual.

Response to microplastic exposure: An exploration into the sea urchin immune cell proteome.

It is now known that the Mediterranean Sea currently is one of the major hotspot for microplastics (MPs; < 5 mm) pollution and that the risks will be even more pronounced in the coming years. Thus, the in-depth study of the mechanisms underlying the MPs toxicity in key Mediterranean organisms, subjected to high anthropic pressures, has become a categorical imperative to pursue. Here, we explore for the first time the sea urchins immune cells profile combined to their proteome upon in vivo exposure (72 h) to different concentrations of polystyrene-microbeads (micro-PS) starting from relevant environmental concentrations (10, 50, 10, 10 MP/L).