Publications by authors named "F Sanchez Ceballos"
Background: Sex estimation is the first stage in the identification of an individual in the forensic context, and can be carried out from bone structures like the mandible. The aim of this study was to estimate sex from metric analysis of the mandible in cone beam computed tomography images (CBCT) of adult Chilean individuals.
Methods: Six mandibular measurements were analysed, five linear and one angular, in CBCT of adult Chilean individuals of both sexes.
Nepal, largely covered by the Himalayan mountains, hosts indigenous populations with distinct linguistic, cultural, and genetic characteristics. Among these populations, the Raute, Nepal's last nomadic hunter-gatherers, offer a unique insight into the genetic and demographic history of Himalayan foragers. Despite strong cultural connections to other regional foragers, the genetic history of this population remains understudied.
View Article and Find Full Text PDFLatin Americans have a rich genetic make-up that translates into heterogeneous fractions of the autosomal genome in runs of homozygosity (F) and heterogeneous types and proportions of indigenous American ancestry. While autozygosity has been linked to several human diseases, very little is known about the relationship between inbreeding, genetic ancestry, and cancer risk in Latin Americans. Chile has one of the highest incidences of gallbladder cancer (GBC) in the world, and we investigated the association between inbreeding, GBC, gallstone disease (GSD), and body mass index (BMI) in 4029 genetically admixed Chileans.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the genetic variance (variome) of the Turkish population, focusing on how admixture and consanguinity influence their genomic makeup related to diseases.
- Exome sequencing data from 773 affected individuals and 643 unaffected relatives revealed that Turkish genomes are closely related to Europeans, with two main subpopulations showing different levels of genetic mixing.
- The analysis identified that higher inbreeding coefficients and longer runs of homozygosity in affected individuals are linked to rare harmful genetic variants, emphasizing their role in hereditary diseases within this population.
Article Synopsis
- The study examined the impact of inbreeding on longevity and fertility within the House of Habsburg, analyzing 124 marriages from around 1450 to 1800 involving 107 men and 124 women.
- Results indicated that higher inbreeding coefficients were linked to earlier age of death for women who had children and increased maternal mortality shortly after childbirth.
- The research concluded that inbreeding significantly affected adult survival and maternal health, marking the first evidence of such impacts on maternal mortality in human populations.