Publications by authors named "F Salvucci"
Article Synopsis
- The study investigates long-COVID, a complex condition with no effective treatments, particularly focusing on cardiovascular symptoms like high heart rate and palpitations linked to mast cell activation (MCA).
- Researchers administered histamine receptor blockers (fexofenadine and famotidine) to 14 patients with long-COVID symptoms over 20 days and compared results with 13 control subjects.
- Results showed that 29% of treated patients experienced complete symptom resolution, with significant improvements in all treated individuals, supporting the idea that targeting histamine receptors may be a viable treatment for long-COVID.
Background And Aims: Despite anticoagulation, usually with heparin, mortality for thromboembolic events in COVID-19 remains high. Clinical efficacy of heparin is due to its interaction with antithrombin (AT) that may be decreased in COVID-19. Therefore, we correlated AT levels with outcomes of COVID-19.
View Article and Find Full Text PDFAbout 40% of diabetic patients with asymptomatic coronary artery disease (CAD) are missed on the basis of the current screening guidelines. Erectile Dysfunction (ED) is a powerful marker of asymptomatic CAD. Aim of the study is to evaluate whether ED can improve the effectiveness of the current guidelines for the screening of CAD in diabetes.
View Article and Find Full Text PDFThe impact of the screening for asymptomatic coronary artery disease (CAD) on the cardiovascular prognosis in diabetes is controversial. The aim of the study was to investigate whether screening for asymptomatic CAD can have an impact on cardiovascular morbidity and mortality in diabetes. In this nonrandomized longitudinal study, 1,189 consecutive type 2 diabetic patients without a history of CAD were evaluated.
View Article and Find Full Text PDFA patient-specific method for the evaluation of wall shear stress in human coronary arteries.
Annu Int Conf IEEE Eng Med Biol Soc
March 2011
Atherosclerotic plaques form at specific sites of the arterial tree, an observation that has led to the "geometric risk factor" hypothesis for atherogenesis. It is accepted that the location of atherosclerotic plaques is correlated with sites subjected to low abnormal values of wall shear stress (WSS), which is in turn determined by the specific geometry of the arterial segment. In particular, the left coronary artery (LCA) is one of the most important sites of plaque formation and its progression may lead to stroke.
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