Publications by authors named "F Salvat"
La encefalopatía traumática crónica es una enfermedad neurodegenerativa resultante de la acumulación de numerosos traumatismos craneoencefálicos, para la cual no existe un diagnóstico en vida definitivo ni un tratamiento específico. Entre los factores de riesgo asociados se encuentran: la exposición a deportes de contacto que predisponen a traumatismos craneoencefálicos clínicos y subclínicos reiterados, la presencia de la apolipoproteína E4 y la edad. A escala microscópica, la lesión patognomónica de la enfermedad implica agregados de proteína tau fosforilada en neuronas, con o sin astrocitos en forma de espina, en las profundidades del surco cortical alrededor de un pequeño vaso sanguíneo, en lo profundo del parénquima y con un patrón irregular, que pueden estar acompañado en ocasiones de otros depósitos de proteínas anormales y prevalentes en otras entidades como placas de beta-amiloide, TDP-43 y/o alfa-sinucleína.
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- - The study investigates how different Dose Voxel Kernels (DVKs) affect absorbed dose (AD) maps in radiopharmaceutical therapy (RPT), aiming to standardize treatment and improve cancer outcomes.
- - Researchers analyzed nine DVKs each for Lutetium (Lu) and Yttrium (Y), calculating variations in absorbed doses using the same time-integrated activity (TIA) maps and software for different patients' treatment cases.
- - The results showed notable differences in the coefficient of variation and maximum percentage differences in absorbed doses, indicating that the choice of DVK significantly impacts dosimetry calculations in clinical settings.
Article Synopsis
- The study aimed to understand how on-field post-concussion symptoms and neurological signs correlate with symptoms reported 72 hours after brain injuries in male rugby players.
- It involved 92 adult rugby players, assessing their symptoms immediately after concussion and again at a follow-up, using several measurement scales.
- Findings showed that symptomatic athletes were over twice as likely to experience post-traumatic amnesia and exhibited higher rates of depression and cognitive/somatic symptoms compared to asymptomatic athletes.
Introduction: Sleep disorders and chronic pain are linked to each other bidirectionally. Both are related to affective disorders, fatigue, depression, anxiety and drug abuse, and have a significant effect on quality of life. The Interdisciplinary Pain Programme (IDP) aims to relieve the patients' pain and improve their functionality by incorporating healthy postural, sleep and nutritional habits, relaxation techniques, physical exercise and cognitive-behavioural mechanisms.
View Article and Find Full Text PDFPurpose: To investigate the capabilities of several variance reduction techniques in the calculation of specific absorbed fractions in cases where the source and the target organs are far away and/or the target organs have a small volume.
Methods: The specific absorbed fractions have been calculated by using the Monte Carlo code PENELOPE and by assuming the thyroid gland as the source organ and the testicles, the urinary bladder, the uterus, and the ovaries as the target ones. A mathematical anthropomorphic phantom, similar to the MIRD-type phantoms, has been considered.