Management Outcomes of Variceal Bleeding in Northern Tanzania: Insights From a Single-Center Retrospective Analysis.

Aims: Due to the expensiveness and unavailability of endoscopy management in Tanzania, the management outcomes of variceal bleeding are unknown. The objective of this study was to assess the management outcomes of patients with variceal bleeding.

Methods: This was a retrospective study conducted between April 2012 and April 2022.

A Spectacular Effect of Tocilizumab in Takayasu Arteritis.

Background: Anti-interleukin-6 receptors (anti-IL-6R) have been a promising new therapeutic alternative in the treatment of Takayasu arteritis.

Case Description: We report the case of a 34-year-old patient with Takayasu arteritis diagnosed in 2017. While she was on corticosteroid and methotrexate, the patient presented twice with clinical and radiological signs of activity, requiring an increase of corticosteroid dose and an increase in the methotrexate dose to 20 mg/week.

Ear, Nose, and Throat sarcoidosis: An etiology that should raise a flag? About two case reports.

Introduction: Sarcoidosis is a chronic inflammatory disease characterized by non-caseous necrotizing epithelial cell granulomas that can affect any organ. Ear, nose, and throat (ENT) involvement is rare. We report two cases of systemic sarcoidosis with ENT onset.

[Impact of therapeutic education on adherence in patients treated with anti-vitamins K].

Introduction: Therapeutic education of the patient (TPE) treated with AVK has improved the safety and efficiency of this treatment by establishing a new doctor-patient relationship. The objective of our study was to assess the impact of a TPE program on adherence in patients treated with AVK.

Methods: We conducted a prospective interventional study between January and September 2020, including two groups of patients hospitalized for a first thromboembolic: a G1 group with conventional service support and a G2 group with an ETP program created during this work.

Elevated Interleukin-21 expression is correlated with systemic sclerosis' severity in Tunisian patients.

Systemic sclerosis (SSc), a rare and lethal autoimmune disorder where patients presents diverse clinical features, therefore unravelling a potential biomarker within a specific cohort is crucial for improving patient care, especially for rare diseases. This study sought to identify potential biomarkers in Tunisian SSc patients. Gene expression analysis of interleukins (IL)-21 and IL-22 in peripheral blood mononuclear cells, using quantitative real-time polymerase chain reaction (qrt-pcr), revealed upregulated IL-21 and downregulated IL-22 in SSc patients compared to healthy controls.