Publications by authors named "F STEPHAN"
Suspected heparin-induced thrombocytopaenia in pulmonary thromboendarterectomy: retrospective cohort.
Interdiscip Cardiovasc Thorac Surg
December 2024
Objectives: Heparin is given for anticoagulation during and after pulmonary thromboendarterectomy for chronic thromboembolic pulmonary hypertension. Our objective was to add to the limited data available on the incidence, management and outcomes of suspected heparin-induced thrombocytopaenia after pulmonary thromboendarterectomy for chronic thromboembolic pulmonary hypertension.
Methods: This retrospective single-centre study included consecutive patients with suspected heparin-induced thrombocytopaenia after pulmonary thromboendarterectomy done in 2005-2018.
Background And Hypothesis: The development of paraclinical tools to assist clinical assessment is already widespread in nearly all other medical specialties. In psychiatry, many efforts are being made to improve management strategies using these new techniques. The first episode psychosis (FEP) is a clinical entity whose evolution after onset is difficult to predict in the current state of our practices.
View Article and Find Full Text PDFObjectives: Prone positioning (PP) has benefits in patients with acute respiratory distress syndrome. The objective of this study was to compare the effects and complications of PP in obese versus non-obese patients with moderate-to-severe acute respiratory distress syndrome after cardiothoracic surgery.
Methods: We retrospectively analysed a database established in 2014-2021 in an intensive care unit.
Polymers with hemiacetal esters integrated in their backbone provide beneficial degradation profiles for (immuno-) drug delivery. However, their fast hydrolysis and low drug loading capacity have limited their applications so far. Therefore, this study focuses on the stability and loading capacity of hemiacetal ester polymers.
View Article and Find Full Text PDFArticle Synopsis
- - Platelet aggregation in the lungs may contribute to thrombocytopenia during acute pulmonary hypertension (PH) decompensation, as observed in lung transplant patients.
- - A study involving 16 patients identified a significantly higher number of platelet aggregates in those experiencing thrombocytopenia compared to control patients without PH.
- - Scanning electron microscopy revealed that the capillaries in the lungs of patients with acute PH decompensation were filled with these platelet aggregates, indicating a potential mechanism for the condition.