Publications by authors named "F S Zanuzzo"

Low-oxygen levels (hypoxia) in aquatic habitats are becoming more common because of global warming and eutrophication. However, the effects on the health/disease status of fishes, the world's largest group of vertebrates, are unclear. Therefore, we assessed how long-term hypoxia affected the immune function of sablefish, an ecologically and economically important North Pacific species, including the response to a formalin-killed Aeromonas salmonicida bacterin.

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Interleukin-1β (IL-1β) is one of the first cytokines expressed during immune responses, and its levels are affected by many factors, including stress. To date, it has only been possible to measure IL-1β transcript (mRNA) expression quantitatively in fish using qPCR. This is because previous studies that measured IL-1β protein concentrations in these taxa used western blotting, which only provides qualitative data.

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Article Synopsis
  • The study investigates how adding dietary cholesterol might help salmon cope with the stress of rising temperatures due to climate change, focusing on its effects on growth and survival.
  • Salmon were subjected to a controlled temperature increase over several weeks while being fed either a regular diet or diets with additional cholesterol.
  • Findings showed that dietary cholesterol had minimal impact on growth and stress levels, though one cholesterol diet slightly reduced survival rates, indicating that some salmon can still thrive in warmer conditions.
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Antibiotics are used to treat bacterial infections in fish aquaculture, and these drugs can interact with immune cells/the immune system and potentially leave fish vulnerable to viral, fungal, parasitic, or other bacterial infections. However, the effects of antibiotics on fish immunity have largely been overlooked by the aquaculture industry. We tested, at 12 and 20 °C, whether tetracycline and florfenicol (the most commonly used antibiotics in commercial aquaculture), affected the Atlantic salmon's capacity to respond to bacterial or viral stimulation.

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Article Synopsis
  • * In a study with Atlantic salmon, the relationship between temperature tolerance and stress response revealed that feed intake remained high even as temperatures increased to 22 °C, and there was no significant difference in stress responses between LR and HR fish at 23.6 °C.
  • * The findings suggest that this salmon population has a high thermal tolerance, challenging the use of critical thermal maximum (CT) as a reliable measure for real-world temperature effects on fish survival and behavior.
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