[Prevalence of arterial hypertension and efficacy of long-term multifactor prophylaxis in some regions of Russia].

Aim: To study prevalence of arterial hypertension (AH) in relation to gender, age, profession, risk factors (RF), RF combination; efficacy of active long-term multifactor prevention among the employees of industrial enterprises in some regions of Russia.

Material And Methods: 14000 males and 20969 females from industrial enterprises of Cheboksary, Pskov, St-Petersburg were examined. 8974 males and 14515 females worked at enterprises of active intervention (EAI) while 1848 males and 1643 females were employed at comparison enterprises.

[Content of trace elements and steroid hormones in blood and tissues of internal organs of rats during an inflammatory process in the bronchi].

Prolonged interrupted inhalation of nitrogen dioxide in a dose of 36.0 +/- 2.2 mg/m3 was attended by definite morphological signs of inflammation in the lungs of rats (hyperplasia of goblet cells, thickening of the basilar membrane, differentiation of ciliated epithelium, etc.

[Content of trace elements and steroid hormones in blood and tissues of internal organs in experimental pulmonary fibrosis induced by intratracheal administration of bleomycetin].

Pulmonary fibrosis was produced in rats by intratracheal administration of bleomycetin. The development of the fibrous process in the lungs was attended by marked reduction of the zinc content in the tissues of the viscera, plasma, and formed elements of the blood, as well as of corticosterone and testosterone in blood plasma. Respiratory insufficiency is a probable cause of the developing zinc-deficiency which leads to disturbed synthesis of steroid hormones.

[Trace elements in the pathogenesis and treatment of chronic bronchitis (a clinico-experimental study)].

Experiments on healthy male rats and those with chronic inflammation in the bronchi (CIB) were made to measure the content of testosterone, estradiol, zinc and copper in the blood and in the liquid of bronchoalveolar lavage (LBAL) as well as in the vitally important organs. Attempts were also made to equalize the content of trace elements by means of medicamentous correction in patients suffering from chronic obstructive bronchitis (COB). In CIB, there was a decrease of testosterone concentration in the blood and of zinc concentration in the plasma and formed elements of the blood, lungs, heart, liver, testes and adrenals (p less than 0.

[Changes in plasma levels of corticosterone, testosterone and estradiol and their receptors in the lung cytosol in experimental fibrosing process in the lungs].

The content of blood plasma corticosterone, testosterone and estradiol, and receptors to corticosteroids, androgens and estrogens in pulmonary cytosol of normal male rats and those with fibrosing process in the lungs were experimentally studied by means of radioimmunoassay. With pulmonary fibrosis, a decrease in the concentration of blood plasma corticosterone and testosterone, and lower content of their pulmonary cytosol receptors to corticosteroids, androgens and estrogens are observed. As testosterone propionate was administered in the course of this experiment, there was a normalization of blood plasma corticosterone levels and those of the pulmonary cytosol receptors to androgens.