Publications by authors named "F S Brinkman"

Article Synopsis
  • The COVID-19 pandemic spurred global efforts to sequence SARS-CoV-2 genomes to monitor its evolution and guide public health decisions, resulting in millions of genome sequences being shared worldwide.
  • The Canadian COVID-19 Genomics Network (CanCOGeN - VirusSeq) launched the Canadian VirusSeq Data Portal to provide open access to genomic sequences and standardized contextual data while adhering to FAIR standards.
  • The portal emphasizes data quality, privacy compliance, and security, and is used alongside tools like Viral AI and the CoVaRR-Net to facilitate ongoing research and analysis of SARS-CoV-2 variants in Canada.
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Article Synopsis
  • - The CHILD Cohort Study is a long-term Canadian research project tracking the health and development of infants from pregnancy until adulthood, focusing on how early life environments affect disease outcomes like asthma and developmental issues.
  • - The study involves detailed measurements and data collection including biological samples, environmental assessments, and psychosocial factors, with a strong participant retention rate over the years.
  • - A sub-cohort was created during the COVID-19 pandemic to examine its impact on families, and the next major assessment phase will occur from 2022 to 2025, contributing valuable insights into chronic diseases and health complexities.
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The COVID-19 pandemic led to a large global effort to sequence SARS-CoV-2 genomes from patient samples to track viral evolution and inform public health response. Millions of SARS-CoV-2 genome sequences have been deposited in global public repositories. The Canadian COVID-19 Genomics Network (CanCOGeN - VirusSeq), a consortium tasked with coordinating expanded sequencing of SARS-CoV-2 genomes across Canada early in the pandemic, created the Canadian VirusSeq Data Portal, with associated data pipelines and procedures, to support these efforts.

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Background: A lack of safety data on postpartum medication use presents a potential barrier to breastfeeding and may result in infant exposure to medications in breastmilk. The type and extent of medication use by lactating women requires investigation.

Methods: Data were collected from the CHILD Cohort Study which enrolled pregnant women across Canada between 2008 and 2012.

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The coronavirus disease 2019 (COVID-19) pandemic has affected all Canadian families, with some impacted differently than others. Our study aims to: (1) determine the prevalence and transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among Canadian families, (2) identify predictors of infection susceptibility and severity of SARS-CoV-2, and (3) identify health and psychosocial impacts of the COVID-19 pandemic. This study builds upon the CHILD Cohort Study, an ongoing multi-ethnic general population prospective cohort consisting of 3,454 Canadian families with children born in Vancouver, Edmonton, Manitoba, and Toronto between 2009 and 2012.

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