Pharmacist prescriber in Italy and possible changes to current legislation: of attitudes among pharmacists, family doctors and users.

Background: In many countries in Europe and in the world, pharmacists are allowed to prescribe or modify therapies. In Italy, the only healthcare professions authorised to prescribe are medical doctors and veterinary surgeons. The extension of the duties of the Italian pharmacist to include prescribing would be extremely important considering the challenges the National health system is facing regarding the shortage of healthcare workers.

Dark chocolate's impact on low-grade endotoxemia in metabolic dysfunction-associated steatohepatitis.

Background And Aims: Cocoa may have prebiotic effects and improve gut barrier function. However, it remains unclear whether dark chocolate can reduce lipopolysaccharide (LPS) levels in patients with metabolic dysfunction-associated steatohepatitis (MASH). This study aims to evaluate the effect of dark chocolate compared to milk chocolate on endotoxemia in patients with MASH.

Impact of Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i) Therapy on Dementia and Cognitive Decline.

Dementia is an age-related syndrome characterized by the progressive deterioration of cognition and capacity for independent living. Diabetes is often associated with cognitive decline and shares similar pathophysiological mechanisms with dementia, such as systemic inflammation, oxidative stress, insulin resistance, and advanced glycation end-products formation. Therefore, adequate diabetes management may reduce the risk of cognitive decline, especially in patients with other comorbidities and risk factors.