[Ranibizumab and exudative age-related macular degeneration: 5-year multicentric functional and anatomical results in real-life practice].

Purpose: The goal of this study was to evaluate five year functional and anatomical outcomes of wet AMD patients treated with ranibizumab according to a pro re nata (PRN) regimen in real-life practice.

Methods: A retrospective, multicentric chart review of 201 eyes of 201 patients who underwent their first ranibizumab intravitreal injection (IVT) between January 1, 2007 and December 31, 2008 was performed. Best-corrected visual acuity (BCVA), central macular thickness (CMT) on SD-OCT, number of IVT and follow-up visits were collected at baseline and during the entire follow-up period of 5 years.

Low-dose proton beam therapy for circumscribed choroidal hemangiomas.

Objective: To evaluate the efficacy and safety of proton beam therapy for complicated circumscribed choroidal hemangiomas.

Methods: The study was a retrospective nonrandomized investigation. Seventeen consecutive patients, referred to the Institut Gustave-Roussy, Villejuif, France, for circumscribed choroidal hemangioma associated with serous retinal detachment were studied.

[Circumstances of choroid and ciliary body melanoma detection].

Purpose: To report and analyze the circumstances of uveal melanoma detection.

Methods: The records of 143 consecutive patients diagnosed in the Ophthalmology Department of Gustave Roussy Institute between September 1994 and September 2001 were analyzed. The study included 66 females and 77 males, aged from 21 to 91 years (mean, 62.

[Bilateral diffuse uveal melanocytic proliferation associated with systemic carcinoma: two case reports].

Diffuse uveal melanocytic proliferation is a rare paraneoplastic syndrome resulting in rapid bilateral visual loss in patients with systemic carcinoma, caused by proliferation of benign melanocytes within the choroid and the ciliary body. More often visual impairment is due to retinal detachment and cataract. The authors report two cases of presumed diffuse uveal melanocytic proliferation.

[Sturge-Weber syndrome: medical management of choroidal hemangiomas].

Purpose: To investigate the outcome of irradiation of complicated choroidal hemangiomas in Sturge-Weber syndrome.

Patients And Methods: The charts of 6 patients (7 eyes) with Sturge-Weber syndrome and choroidal hemangiomas were reviewed. An exudative retinal detachment was the indication for treatment in all cases.