Publications by authors named "F Roudot-Thoraval"
Article Synopsis
- * It includes data from 413 patients (142 HBV-HDV and 271 HBV monoinfected) and finds that those with HBV-HDV are generally younger and experience a significantly higher incidence of HCC over 5 years compared to HBV-only patients.
- * The results indicate that HDV is an independent risk factor for the development of HCC in patients with cirrhosis, highlighting its important role regardless of HBV
Article Synopsis
- * Out of 230 patients evaluated, TE showed strong diagnostic accuracy for detecting cirrhosis and advanced fibrosis, with area under the receiver operating characteristic curves of 0.88 and 0.86, outperforming other non-invasive tests.
- * The findings suggest that LSM values above 10 kPa indicate a high probability of advanced fibrosis, while values below 6 kPa almost completely rule out significant fibrosis, necessitating further discussion for values between 6 and 10 kPa.
Background And Aims: Chronic hepatitis D infection is the most severe form of viral hepatitis and can rapidly progress to cirrhosis or hepatocellular carcinoma. Despite recommendations for systematic screening of hepatitis B surface antigen (HBsAg)-positive individuals, data from real-world studies have reported a low frequency of hepatitis D (or delta) virus (HDV) screening. Our cross-sectional analysis evaluated the diagnostic cascade for hepatitis D infection in tertiary centres and described the characteristics of HDV-positive patients.
View Article and Find Full Text PDFObjectives: Migrants from high HIV, hepatitis B virus (HBV) or hepatitis C virus (HCV) endemicity regions have a great burden of these infections and related diseases in the host countries. This study aimed to assess the predictive capacity of the Test Rapide d'Orientation Diagnostique (TROD) Screen questionnaire for HIV, HBV and HCV infections among migrants arriving in France.
Design: An observational and multicentre study was conducted among migrants.
Background And Aim: Germline mutations of telomere-related genes (TRG) induce multiorgan dysfunction, and liver-specific manifestations have not been clearly outlined. We aimed to describe TRG mutations-associated liver diseases.
Approach And Results: Retrospective multicenter analysis of liver disease (transaminases > 30 IU/L and/or abnormal liver imaging) in patients with TRG mutations.