Publications by authors named "F Roth-Walter"
Background: Iron-deficiency is associated with increased morbidity and mortality in non-communicable diseases. However, iron parameters are rarely assessed in dogs. Here, we aimed to assess and correlate iron parameters in dogs suffering from Canine Atopic Dermatitis (CAD) compared to non-atopic, healthy dogs.
View Article and Find Full Text PDFNutritional Considerations of Plant-Based Diets for People With Food Allergy.
Clin Exp Allergy
November 2024
Article Synopsis
- Plant-based diets (PBD) are gaining popularity due to increased awareness of climate change and health, with many dietary organizations supporting well-planned versions that may eliminate some or all animal products.
- Individuals with food allergies (FA) who follow a PBD need careful monitoring to prevent nutritional deficiencies that can affect growth in children and weight gain in adults.
- Healthcare providers should focus on ensuring adequate intakes of essential nutrients like protein, fats, vitamins (A, B2, B12, D), and minerals (iron, zinc, iodine, calcium, magnesium) for patients on PBDs with food allergies.
Background: Consumption of ultra-processed foods [UPFs] may be associated with negative health outcomes. Limited data exist regarding the potential role of UPFs in the occurrence of allergic diseases. The underlying mechanisms underpinning any such associations are also poorly elucidated.
View Article and Find Full Text PDFArticle Synopsis
- Malnutrition, especially involving protein and micronutrient deficiencies, is often seen in individuals with allergic conditions like dermatitis and asthma, which can worsen allergic sensitization.
- Deficiencies can lead to increased Th2 inflammation, causing the immune system to respond in ways that limit nutrient absorption as if the body is fighting an infection.
- The review discusses how allergens can bind to nutrients, affecting their availability and potentially triggering allergies, while also highlighting that in nutrient-rich situations, these same allergens can support immune health.
Background: We investigated the biological function of the mould allergen Alt a 1 as a carrier of micronutrients, such as the vitamin A metabolite retinoic acid (RA) and the influence of RA binding on its allergenicity in vitro and in vivo.
Methods: Alt a 1-RA complex formation was analyzed in silico and in vitro. PBMCs from Alternaria-allergic donors were stimulated with Alt a 1 complexed with RA (holo-Alt a 1) or empty apo-Alt a 1 and analyzed for cytokine production and CD marker expression.