Publications by authors named "F Rongioletti"
Anorectal melanoma (ARM) is a rare malignancy often associated with a poor prognosis due to its late diagnosis and aggressive biological behavior. This review aims to comprehensively investigate ARM's diagnosis, management, and treatment, emphasizing its clinical characteristics, laboratory findings, and implications for patient prognosis. A systematic literature search was conducted in PubMed, Embase, and Cochrane CENTRAL databases from inception to 1 July 2024.
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- Intravenous immunoglobulin (IVIG) therapy shows promise for treating various dermatological autoimmune diseases due to its ability to modulate the immune system and low risk of severe side effects.
- The exact mechanism of how IVIG works in autoimmune diseases is still debated, but it involves neutralizing harmful autoantibodies and preventing tissue damage.
- While IVIG is primarily used off-label for conditions like dermatomyositis and systemic sclerosis, a key study (ProDERM 2022) demonstrated its effectiveness specifically for dermatomyositis, and it is commonly used as first-line treatment for scleromyxedema.