Consensus based recommendations for diagnosis and medical management of Poland syndrome (sequence).

Background: Poland syndrome (OMIM: 173800) is a disorder in which affected individuals are born with missing or underdeveloped muscles on one side of the body, resulting in abnormalities that can affect the chest, breast, shoulder, arm, and hand. The extent and severity of the abnormalities vary among affected individuals.

Main Body: The aim of this work is to provide recommendations for the diagnosis and management of people affected by Poland syndrome based on evidence from literature and experience of health professionals from different medical backgrounds who have followed for several years affected subjects.

Day-to-day variability of electrocardiographic diagnosis of left ventricular hypertrophy in hypertensive patients. Influence of electrode placement.

Objective: Although electrocardiography (ECG) is recommended in all subjects with hypertension, no information is available on the influence exerted by random changes in the placement of electrodes on the day-to-day variability of ECG criteria for diagnosis of left ventricular hypertrophy (LVH).

Methods: In a multicentre, randomized study, two standard 12-lead ECG were recorded, 24 h apart, from 276 consecutive hypertensive patients (mean age 65 +/- 12 years, 49.6% men).

Clinical and pharmacological profile in a clenbuterol epidemic poisoning of contaminated beef meat in Italy.

Long-acting beta adrenergic agonists, such as clenbuterol accumulate in the liver, but not meat of treated farm animals, and result in epidemic poisonings in consumers. We describe an outbreak of poisoning in 15 people, following the consumption of meat. Clinical symptoms (distal tremors, palpitations, headache, tachipnoea-dyspnoea, and also moderate hyperglycaemia, hypokalemia and leucocytosis) were seen in nine hospitalised patients, starting about 0.

Prognostic value of 24-hour blood pressure in pregnancy.

Context: Elevated blood pressure (BP) measured at the physician's office may reflect true hypertension or white coat hypertension (WCH). The prognostic value of WCH among pregnant women is unknown.

Objective: To assess the prognostic value of WCH in pregnancy.

Twenty four-hour ambulatory blood pressure monitoring in women with pre-eclampsia.

The aim of our study was to evaluate by means of ambulatory 24 h monitoring the diurnal systolic (SBP) and diastolic (DBP) blood pressure profiles in a group (n = 18) of gravid patients with pre-eclampsia compared with a group (n = 17) of healthy control subjects matched for age and week of gestation to assess whether: (i) ambulatory BP is also raised in pre-eclampsia; (ii) the increase of BP, if present, occurs to the same extent during both daytime and night; and (iii) a blunted BP pattern is consistently present in pre-eclampsia. BP was recorded at intervals of 15 min for 25 h using a TM2420 non-invasive pressurometer. The presence of a circadian rhythm of BP was assessed by cosinor analysis.