Higher rates of fully preserved posterior cruciate ligament in total knee arthroplasty using a double tibial cut: a prospective randomized controlled trial.

Purpose: In cruciate retaining total knee arthroplasty, posterior cruciate ligament damage may occur during tibial cutting. A prospective randomized study was conducted to investigate whether a novel tibial cutting technique was more effective than the currently used techniques.

Materials And Methods: Patients undergoing cruciate retaining total knee arthroplasty were recruited in a prospective, randomized, controlled trial.

Revisiting the tibial crest as reference for the mechanical alignment of the tibial component in total knee arthroplasty: a cadaveric study on Caucasian tibiae.

Purpose: The accuracy of the tibial crest (TC) in guiding the mechanical alignment of the tibial component in total knee arthroplasty (TKA) has been investigated in a few studies on Asian patients. No study analyzed the anatomical variants of the TC. We analyzed the morphological types of the TC in cadaveric tibiae of Caucasian subjects and assessed whether the TC may be considered an accurate guide for the mechanical alignment of the tibial component in TKA.

Is there any difference between tapered titanium stems with similar geometry and hydroxyapatite coating?

Purpose: Several tapered stems with similar geometry and extensive hydroxyapatite coating have recently been introduced. It is not clear, however, whether they share the same design or whether they exhibit any difference that might affect their clinical performances. In this study, we analysed five tapered stems fully coated with hydroxyapatite to establish whether they exhibit similar geometric features and may therefore be used indifferently when a cementless stem is indicated.

The native coronal orientation of tibial plateaus may limit the indications to perform a kinematic aligned total knee arthroplasty.

Purpose: To investigate the coronal alignment of tibial plateaus in normal and osteoarthritic knees and to simulate the effects of a tibial cut performed in total knee arthroplasty (TKA) using a kinematic alignment technique with standard instrumentation.

Methods: The coronal alignment of tibial plateaus was measured in three groups including group 1 (reference group), 50 cadaveric tibiae showing no evidence of degenerative changes of tibial plateaus; group 2, 49 patients who underwent MR of the knee, showing no or mild degenerative changes of the knee joint and, group 3, 54 patients with knee osteoarthritis who underwent computer-assisted total knee arthroplasty.

Results: The coronal alignment of tibial plateaus averaged 2.

Telomere length is independently associated with age, oxidative biomarkers, and sport training in skeletal muscle of healthy adult males.

In skeletal muscle, which mainly contains postmitotic myonuclei, it has been suggested that telomere length remains roughly constant throughout adult life, or shortens in response to physiopathological conditions in muscle diseases or in the elderly. However, telomere length results from both the replicative history of a specific tissue and the exposure to environmental, DNA damage-related factors, therefore the predictive biological significance of telomere measures should combine the analysis of the various interactive factors. In the present study, we analysed any relationship between telomere length [mean and minimum terminal restriction fragment (TRF) length] chronological age, oxidative damage (4-HNE, protein carbonyls), catalase activity, and heat shock proteins expression (αB-crystallin, Hsp27, Hsp90) in semitendinous muscle biopsies of 26 healthy adult males between 20 and 50 years of age, also exploring the influence of regular exercise participation.