Isolation, characterization, quantification and antioxidant activity of compounds from .

In the present study, 85% aqueous ethanol extract of stem bark (MESB) showed the isolation of six bioactive compounds including myricanone (), myricanol-5-O-β-D-glucopyranoside (), myricetin (), myricolol (), β-sitosterol (), and β-sitosterol-D-glucoside (). The HPLC approach revealed as a key bioactive compound, with a 69% abundance in the crude ethanol (CE) extract. Furthermore, the CE was assessed for antioxidant activity using DPPH and hydroxyl radical tests, while purified compounds were examined for total antioxidant capacity using cyclic voltammetry and verified using the density functional theory (DFT) method.

Pattern of Uveitis in a Tertiary Care Eye Hospital Setting in Pakistan: A Comprehensive Analysis.

Purpose: To determine the patterns of uveitis evident in patients presenting at the Uveitis Department of a tertiary care eye hospital located in Karachi, Pakistan.

Study Design: Prospective cross-sectional study.

Location And Duration Of Study: This study was conducted at Layton Rahmatullah Benevolent Trust (LRBT) Tertiary Teaching Eye Hospital-Korangi, Karachi, Pakistan from August 2020 to July 2023.

Comparative and combination study of simvastatin alone and in combination with Beta vulgaris in hyperlipidemia patients.

Phytomedicine is gaining acceptance as well preference in health care management for various diseases. Drug combinations are mostly used clinically for hyperlipidemia, as single-agent therapy is insufficient. Statins remain the cornerstone of hyperlipidemia.

Synthesis of isoniazid derivatives and evaluation of their α-chymotrypsin inhibitory effect through in silico guided in vitro studies.

Alpha-chymotrypsin is a serine protease. Its overexpression is responsible for several ailments, such as chronic obstructive pulmonary disease, autoimmune diseases, pancreatitis, and colon cancers. Therefore, the discovery of potent α-chymotrypsin inhibitors is essential for the treatment of the aforementioned ailments.