Publications by authors named "F Rikki Canevari"

Purpose: Immunoglobulin G4-related disease (IgG4-RD) is a complex systemic fibroinflammatory condition with different clinical manifestations affecting multiple organ systems. Despite its rarity, the disease presents diagnostic and therapeutic challenges due to its mimicry of malignancies and other immune-mediated disorders. The 2019 American College of Rheumatology/European League Against Rheumatism Classification Criteria for IgG4-Related Disease is the current state of art to confirm the diagnosis of IgG4-RD even in the absence of histological analysis.

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A 9-year-old girl presented to our neurosurgery clinic complaining of visual disturbances for a week. Magnetic resonance imaging showed an extensive sellar lesion with suprasellar involvement and compression of the optic chiasm. Based on these findings, a cystic craniopharyngioma, a pituitary macroadenoma and - less likely - a Rathke's cleft cyst were considered as differential diagnoses.

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Article Synopsis
  • Chronic rhinosinusitis with nasal polyps (CRSwNP) significantly affects quality of life, and the main goal of its management is to achieve consistent disease control.
  • A survey of otorhinolaryngologists in Italy revealed a consensus on the limitations of existing guidelines and the need for better implementation in clinical practice, emphasizing the importance of clinical symptoms from the patient's perspective.
  • Respondents highlighted key symptoms such as nasal obstruction and loss of smell, while advocating for a specific tool to accurately define disease control, especially in the context of new biologic treatments.
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Chronic rhinosinusitis (CRS) is a complex and heterogeneous disorder whose etiopathogenetic picture is not yet completely known and is classically divided into CRS with (CRSwNP) and without nasal polyps (CRSsNP). But today the distinction is made with type 2 and nontype 2 variants. A rational and defined pathway for the diagnosis of chronic rhinosinusitis is an indispensable means to be able to arrive at a correct identification of the patient.

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