First indisputable fossil Ilex (Aquifoliales: Aquifoliaceae) flower found in Baltic amber.

The genus Ilex (holly) in the monotypic family Aquifoliaceae contains more than 600 species distributed worldwide. Pollen fossils and macrofossils of fruits of Ilex are known from the late Cretaceous (90 Ma) and verified leaves from the upper Miocene (10 Ma), but until now only a few more or less incomplete flower fossils have been suggested as referable to this genus. This paper reviews the fossil flowers earlier attributed to Ilex and presents a complete and indisputable staminate Ilex flower from Baltic amber (34-38 Ma) examined in detail with synchrotron X-ray tomography.

Using AI to Identify Unremarkable Chest Radiographs for Automatic Reporting.

Background Radiology practices have a high volume of unremarkable chest radiographs and artificial intelligence (AI) could possibly improve workflow by providing an automatic report. Purpose To estimate the proportion of unremarkable chest radiographs, where AI can correctly exclude pathology (ie, specificity) without increasing diagnostic errors. Materials and Methods In this retrospective study, consecutive chest radiographs in unique adult patients (≥18 years of age) were obtained January 1-12, 2020, at four Danish hospitals.

DCE-CT parameters as new functional imaging biomarkers at baseline and during immune checkpoint inhibitor therapy in patients with lung cancer - a feasibility study.

Background: With the development of immune checkpoint inhibitors for the treatment of non-small cell lung cancer, the need for new functional imaging techniques and early response assessments has increased to account for new response patterns and the high cost of treatment. The present study was designed to assess the prognostic impact of dynamic contrast-enhanced computed tomography (DCE-CT) on survival outcomes in non-small cell lung cancer patients treated with immune checkpoint inhibitors.

Methods: Thirty-three patients with inoperable non-small-cell lung cancer treated with immune checkpoint inhibitors were prospectively enrolled for DCE-CT as part of their follow-up.

Occupational exposure to respirable crystalline silica and incident idiopathic interstitial pneumonias and pulmonary sarcoidosis: a national prospective follow-up study.

Background: Respirable crystalline silica is a well-known cause of silicosis but may also be associated with other types of interstitial lung disease. We examined the associations between occupational exposure to respirable crystalline silica and the risk of idiopathic interstitial pneumonias, pulmonary sarcoidosis and silicosis.

Methods: The total Danish working population was followed 1977-2015.

Risk of hypersensitivity pneumonitis and other interstitial lung diseases following organic dust exposure.

Background: Organic dust is associated with hypersensitivity pneumonitis, and associations with other types of interstitial lung disease (ILD) have been suggested. We examined the association between occupational organic dust exposure and hypersensitivity pneumonitis and other ILDs in a cohort study.

Methods: The study population included all residents of Denmark born in 1956 or later with at least 1 year of gainful employment since 1976.