Publications by authors named "F Rabbia"

Antihypertensive pharmacological therapy is often characterized by a coadministration of different classes of drugs. Therefore, analytical methods allowing the simultaneous quantification of many drugs are needed for therapeutic drug monitoring (TDM) purposes in this context. In particular, TDM represents a useful tool to discriminate poor adherence from real cases of resistant hypertension.

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Introduction: Renovascular hypertension (RVH) remains underdiagnosed despite its significant cardiovascular and renal morbidity.

Aim: This survey investigated screening and management practices for RVH among hypertensive patients in Italian hypertension centres in a real-life setting. Secondary, we analysed the current spread of renal denervation (RDN) and the criteria used for its eligibility.

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Article Synopsis
  • The study investigated how the COVID-19 pandemic affected blood pressure control in patients with hypertension using ambulatory blood pressure monitoring (ABPM).
  • Data were compared between two groups: patients measured before the pandemic and those measured during it, with a total of 704 pandemic patients and 916 prepandemic patients included in the analysis.
  • Results showed that during the pandemic, patients had higher blood pressure readings and a greater prevalence of uncontrolled hypertension, highlighting the need for strategies to manage blood pressure during such crises.
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Article Synopsis
  • Hyperkalemia is a common electrolyte imbalance, impacting around 7.3% of patients with hypertension, often due to medications or chronic kidney disease.
  • A small percentage (0.04%) of these patients had familial hyperkalemic hypertension (FHH), with higher prevalence in those with unexplained hyperkalemia.
  • Hyperkalemia is linked to increased cardiovascular risks, emphasizing the need for early diagnosis and tailored treatment strategies for effective management.
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Drug allergy and intolerance are increasingly recognized as significant public health concerns, leading to adverse reactions in patients undergoing pharmacological treatments. Multiple drug intolerance syndrome (MDIS), characterized by adverse reactions to at least three different drug classes without a clear immunological mechanism, poses a substantial challenge, particularly in hypertensive patients. Despite its link to suboptimal adherence and uncontrolled blood pressure, MDIS in the context of hypertension remains insufficiently explored.

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