Direct amplification and genotyping of Dientamoeba fragilis from human stool specimens.

Dientamoeba fragilis is a globally occurring parasite that has been recognized as a causative agent of gastrointestinal symptoms. A single-round PCR was developed to detect D. fragilis DNA directly from human stool samples.

Neuro-psychiatric effects of antimalarials.

Objective: To study the neuro-psychiatric adverse effects of antimalarial drugs.

Setting: Persons who visited a Travel Clinic in Rotterdam over a period of 3 months.

Design: Prospective cohort study on 394 persons taking mefloquine, 493 persons taking proguanil and 340 persons not taking antimalarial drugs who visited Africa, South America, Asia, or the Middle East.