Before items can be implemented in a test, the item characteristics need to be calibrated through pretesting. To achieve high-quality tests, it's crucial to maximize the precision of estimates obtained during item calibration. Higher precision can be attained if calibration items are allocated to examinees based on their individual abilities.
View Article and Find Full Text PDFBackground: Excessive anterior pelvic tilt (APT) in youth with cerebral palsy (CP) may be associated with back pain and functional limitations. This study aimed to determine risk factors for excessive APT and significant change during childhood in ambulatory youth with CP.
Methods: This institutional review board-approved retrospective study identified youth with bilateral spastic CP and multiple gait analyses.
Introduction: Environmental exposures are known to affect the health and well-being of populations throughout the life course. Children are particularly susceptible to environmental impacts on educational and health outcomes as they spend more time in their local environments compared to adults. In England, no national, longitudinal dataset linking information about the physical and social environment in and around homes and schools to children's health and education outcomes currently exists.
View Article and Find Full Text PDFDysregulation of histones has been implicated in several medical conditions, including various cancers and neurodegenerative disorders. Histone-specific biosensors are key in detecting and quantifying them, advancing our understanding of chromatin dynamics and epigenetic regulation for potential breakthroughs in cancer research and personalized medicine. The focus of this paper is on quantifying a biosensor's ability to distinguish between Human Histones (H4) and non-target analytes.
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