Publications by authors named "F R Gutierrez"

This study aimed to examine the education and training needs of health care practitioners (HCPs) in the Philippines who encounter lung oligometastatic cancer patients. Lung oligometastatic disease is among the most common sites for cancer spread and has the most established practices for treating oligometastases. A modified version of the Hennessy-Hicks Training Needs Assessment Questionnaire was administered online to HCPs working in private and public centers in the Philippines.

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Importance: Fostamatinib, a spleen tyrosine kinase inhibitor, has been reported to improve outcomes of COVID-19.

Objective: To evaluate the efficacy and safety of fostamatinib in adults hospitalized with COVID-19 and hypoxemia.

Design, Setting, And Participants: This multicenter, phase 3, placebo-controlled, double-blinded randomized clinical trial was conducted at 41 US sites and 21 international sites between November 17, 2021, and September 27, 2023; the last follow-up visit was December 31, 2023.

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Article Synopsis
  • Antarctica's microbial communities have gained interest for their potential in industrial applications, especially through advances in sequencing technologies that help study unculturable microorganisms.
  • Researchers analyzed soils from seven sub-Antarctic islands and Union Glacier using a metagenomic approach, finding that Actinobacteria and Cyanobacteria dominated the microbial community.
  • Genes related to the degradation of various pollutants and industrial enzymes suitable for low-temperature activities were prevalent, indicating that Antarctic soils could be valuable sources for industrial enzyme development.
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Background: The understanding of how pharyngeal pressure is transmitted to the trachea with high-flow nasal cannula (HFNC) implementation and the behavior of tracheal pressure in the presence of mouth leaks remains limited. This study aimed to assess the impact of HFNC administration on tracheal pressure by comparing measurements taken with open and closed mouth with varying flows.

Methods: A crossover study was conducted between March 2019 and June 2023.

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