Publications by authors named "F R Beyer"

Background: The shoulder is the joint most often affected by dislocations. It is known that bony defects of the glenoid and/or humerus can lead to recurrent dislocations even after arthroscopic shoulder stabilization. To prevent recurrent instability, it appears reasonable to reduce fresh and larger Hill-Sachs lesions (off-track lesions).

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  • The field of social neuroscience seeks effective methods to study social interactions and cognition in labs, with perspective taking being a crucial aspect.
  • A new paradigm, the ball detection task, allows participants to form differing beliefs about a target stimulus alongside a virtual agent, showing limited reaction to incongruence in beliefs.
  • In an online study, both behavioral and neural evidence failed to support perspective taking, suggesting that current social cognition paradigms may lack reliability and call for simpler, more ecologically valid approaches.
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  • - White matter hyperintensities indicate damage in the brain's white matter, which can lead to brain shrinkage and is linked to dementia; a study of over 51,000 people found that larger volumes of these hyperintensities correspond to thinner brain cortex.
  • - Researchers identified 20 significant genetic loci related to white matter hyperintensities that affect genes involved in brain cell types known to support vascular health and neuronal function; some of these genes play roles in processes like axonal structure and transport within the brain.
  • - The genetic traits tied to white matter issues were linked to cardiovascular health, neurodegeneration markers, and poorer cognitive performance, with a polygenic risk score effectively predicting dementia risk in a separate large
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Background: Neonates with suspected sepsis are commonly treated with gentamicin, an aminoglycoside. These antibiotics are associated with high risk of ototoxicity, including profound bilateral deafness, in people with the m.1555A>G mitochondrial genetic variant.

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  • Alzheimer's disease (AD) is marked by cognitive decline and specific brain atrophy, particularly affecting the medial temporal lobes, yet hypothalamic atrophy in AD has been less studied, especially in its early stages.
  • * Researchers analyzed hypothalamic volume using advanced MRI techniques on a sample of 175 participants including cognitively normal individuals, those with mild cognitive impairment, and AD patients, aiming to explore structural changes associated with the disease.
  • * Results indicated that hypothalamic atrophy occurs in both early and late stages of AD, showing relationships with key brain regions involved in autonomic function, though group differences in hypothalamic structure were not significant.
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