Publications by authors named "F Pousset"

Article Synopsis
  • The study investigates heart failure (HF) hospitalization in France post-pandemic, focusing on incidence, prevalence, patient characteristics, management, and outcomes based on sex, age, and socio-economic status.
  • Utilizing a comprehensive health care database, findings reveal a prevalence rate of 1.7% in France, with an overall decrease in acute HF decompensation incidence since 2012, particularly among men under 45.
  • Despite improvements in management and a decline in one-year rehospitalization rates, one-year mortality rates remain high, especially among younger women and the most deprived areas.
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Article Synopsis
  • - In 2022, France recorded 181,178 hospitalizations for heart failure (HF), yielding a prevalence rate of 2.6% among adults, while hospitalization rates were notably higher in socioeconomically deprived areas.
  • - The overall hospital fatality rate for HF was 10.2%, with a significant increase to 34.0% within a year; however, only 20.1% of patients were admitted to rehabilitation within six months.
  • - The findings highlight the need for improved cardiovascular prevention strategies and adaptations in healthcare services across different regions in France, emphasizing the importance of better adherence to treatment guidelines.
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Aims: Inherited cardiomyopathies are relatively rare but carry a high risk of cardiac maternal morbidity and mortality during pregnancy and postpartum. However, data for risk stratification are scarce. The new CARPREG II score improves prediction of prognosis in pregnancies associated with heart disease, though its role in inherited cardiomyopathies is unclear.

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Background And Objectives: Friedreich ataxia (FRDA) is an autosomal recessive ataxia with no approved treatments. Leriglitazone is a selective peroxisome proliferator-activated receptor γ agonist that crosses the blood-brain barrier and, in preclinical models, improved mitochondrial function and energy production. We assessed effects of leriglitazone in patients with FRDA in a proof-of-concept study.

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BackgroundDuring the COVID-19 pandemic, national and local measures were implemented on the island of Mayotte, a French overseas department in the Indian Ocean with critical socioeconomic and health indicators.AimWe aimed to describe the COVID-19 outbreak in Mayotte from March 2020 to March 2021, with two waves from 9 March to 31 December 2020 and from 1 January to 14 March 2021, linked to Beta (20H/501Y.V2) variant.

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