Publications by authors named "F Pierron"

Article Synopsis
  • Understanding habitat quality is crucial for tracking pollution effects on aquatic ecosystems, especially for early fish life stages which are sensitive indicators of environmental health.
  • The ex-situ exposure method was developed to study fish and crustacean responses to water quality under controlled conditions, minimizing external factors like temperature and oxygen levels.
  • Findings from the Garonne River study revealed that poor water quality significantly affected Japanese medaka embryo survival, while Gammarus fossarum showed altered feeding rates without impacts on their embryo survival, highlighting species-specific sensitivities to pollution.
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Sex ratio variation is a key topic in ecology, because of its direct effects on population dynamics and thus, on animal conservation strategies. Among factors affecting sex ratio, types of sex determination systems have a central role, since some species could have a sex determined by genetic factors, environmental factors or a mix of those two. Yet, most studies on the factors affecting sex determination have focused on temperature or endocrine-disrupting chemicals (EDCs), and much less is known regarding other factors.

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There is increasing evidence for the involvement of epigenetics in sex determination, maintenance, and plasticity, from plants to humans. In our previous work, we reported a transgenerational feminization of a zebrafish population for which the first generation was exposed to cadmium, a metal with endocrine disrupting effects. In this study, starting from the previously performed whole methylome analysis, we focused on the gene and hypothesized that it could be involved in sex differentiation and Cd-induced offspring feminization.

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Microbubbles utilize high-frequency oscillations under ultrasound stimulation to induce a range of therapeutic effects in cells, often through mechanical stimulation and permeabilization of cells. One of the largest challenges remaining in the field is the characterization of interactions between cells and microbubbles at therapeutically relevant frequencies. Technical limitations, such as employing sufficient frame rates and obtaining sufficient image resolution, restrict the quantification of the cell's mechanical response to oscillating microbubbles.

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Article Synopsis
  • * The study introduces a new technique called the image-based ultrasonic cell shaking test, allowing for controllable deformation of cells and real-time quantification of their responses to ultrasonic vibrations.
  • * This method combines ultrasonic vibrations with high-speed microscopic imaging to analyze cell deformation and subsequent biological responses, potentially enhancing knowledge of ultrasonic surgical cutting and mechanobiological pathways.
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