Early life microbial succession in the gut follows common patterns in humans across the globe.

Characterizing the dynamics of microbial community succession in the infant gut microbiome is crucial for understanding child health and development, but no normative model currently exists. Here, we estimate child age using gut microbial taxonomic relative abundances from metagenomes, with high temporal resolution (±3 months) for the first 1.5 years of life.

Sociopolitical antecedents influencing COVID-19 vaccine uptake in Pima County, Arizona.

Introduction: Vaccine hesitancy among marginalized populations particularly in the Hispanic community over the course of the COVID-19 pandemic has presented as a public health issue. This study examined the relationship between political affiliation and vaccination decisions of Hispanic adults in Pima County, Arizona.

Methods: Between January and October 2022, 623 participants completed surveys in English or Spanish after completing informed consent process.

Evaluation of Microleakage and Shear Bond Strength of Two Different Calcium-based Silicate Indirect Pulp Capping Agents When Restored with Glass Ionomer Cement and Composite Resin Restoration: A Comparative Study.

Background: Indirect pulp therapy (IPT) is a conservative treatment approach that leaves the deepest caries adjacent to the pulp undisturbed in an effort to avoid pulp exposure. The result of IPT is primarily dependent on the biocompatibility, sealing capacity, adaptability of the overlying restoration to underlying dentin, and strength of the liner material utilized.

Aim: To evaluate shear bond strength (SBS) and microleakage of mineral trioxide aggregate (e-MTA) and biodentine when restored with glass ionomer cement (GIC) and composite resin after their initial set time.

Safety, effectiveness and immunogenicity of heterologous mRNA-1273 boost after prime with Ad26.COV2.S among healthcare workers in South Africa: The single-arm, open-label, phase 3 SHERPA study.

Limited studies have been conducted on the safety and effectiveness of heterologous COVID-19 vaccine boosting in lower income settings, especially those with high-HIV prevalence., The Sisonke Heterologous mRNA-1273 boost after prime with Ad26.COV2.

Pyrfume: A window to the world's olfactory data.

Advances in theoretical understanding are frequently unlocked by access to large, diverse experimental datasets. Our understanding of olfactory neuroscience and psychophysics remain years behind the other senses, in part because rich datasets linking olfactory stimuli with their corresponding percepts, behaviors, and neural pathways remain scarce. Here we present a concerted effort to unlock and unify dozens of stimulus-linked olfactory datasets across species and modalities under a unified framework called Pyrfume.