Publications by authors named "F Palmese"

Purpose: Sarcopenia is a progressive and generalized skeletal muscle disorder, involving the accelerated loss of skeletal muscle mass and function, associated with an increased probability of adverse outcomes including falls. The circadian timing system may be involved in molecular pathways leading to sarcopenia in older adults. We aimed to provide an updated and systematic map of the available evidence on the role of the circadian timing system in sarcopenia, specifically related to the aging process.

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Purpose: Caregivers of people with dementia often face a demanding care burden that may lead to adverse physical and psychological outcomes. Wearable sensors are becoming a valuable tool for preventive care. We aimed to provide the first systematic map of the published evidence on the use of wearable sensors to monitor caregivers of people with dementia.

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Article Synopsis
  • A multivariable logistic regression model was developed to predict the likelihood of 1-year readmission to the emergency department for patients with acute alcohol intoxication, using data from 3,304 patients at a hospital in Italy.
  • The model initially included various predictors such as age, sex, and several health and social factors, and underwent optimization to improve its simplicity while maintaining accuracy.
  • The final reduced model showed strong predictive performance and should be tested in other patient groups to confirm its clinical usefulness.
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Background And Aims: The PREDICT study recently showed that acutely decompensated (AD) patients with cirrhosis can present three different clinical phenotypes in the 90 days after admission: (1) pre-ACLF, developing acute-on-chronic liver failure (ACLF); (2) unstable decompensated cirrhosis (UDC), being re-admitted for AD without ACLF and (3) stable decompensated cirrhosis (SDC), not presenting readmission or ACLF. This study aimed to externally validate the existence of these three distinct trajectories and to identify predictors for the occurrence of each trajectory.

Methods: Baseline data, 3-month ACLF and readmission incidence and 1-year survival were analysed in a prospective cohort of patients admitted for AD.

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Article Synopsis
  • The study focuses on patients with decompensated cirrhosis who frequently require unscheduled hospital readmissions, aiming to understand the causes and predict factors linked to 30-day readmissions after an initial hospitalization for acute decompensation.
  • Out of 329 patients analyzed, more than half (55%) were readmitted within a year, with common causes being hepatic encephalopathy, ascites, and infections, and 30% of those experienced multiple readmissions.
  • Key findings suggest that a low hemoglobin level (≤8.7 g/dl) and a higher MELD-Na score (>16) at discharge are significant predictors of early readmission, highlighting the need for targeted follow-up care for affected patients
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