Publications by authors named "F P Kapczinski"

Article Synopsis
  • Arketamine (R-ketamine) has shown potential for prolonged antidepressant effects and better safety compared to esketamine (S-ketamine), though it has been less studied.
  • A review of 20 studies with 410 subjects indicated arketamine's effectiveness for pain management and depression, but many studies were small and informal.
  • While arketamine generally has a favorable safety profile, more substantial research is needed to better understand its therapeutic potential and proper clinical usage.
View Article and Find Full Text PDF

Objective: This study aims to conduct an overview on the comparative efficacy of valproate in acute mania, bipolar depression and maintenance treatment of bipolar disorder (BD).

Method: We performed an overview of systematic reviews with meta-analyses of randomised controlled trials (RCTs), registered in PROSPERO (CRD42024497749). We searched Medline and Cochrane Database of Systematic Reviews.

View Article and Find Full Text PDF

The Brazilian Academy of Sciences commissioned a report on mental health to develop strategies for addressing mental health challenges in the post-pandemic world. These strategies should be evidence-based, culturally sensitive, resource-efficient, and promote equity, while being tailored to specific contexts. The report's proposals are meant for discussion among S20 participating Academies of Sciences, serving as a collection of ideas to influence global mental health policies, rather than mandatory guidelines.

View Article and Find Full Text PDF