Eur Arch Psychiatry Clin Neurosci
December 2024
BMJ Open
November 2024
Objective: This study aims to conduct an overview on the comparative efficacy of valproate in acute mania, bipolar depression and maintenance treatment of bipolar disorder (BD).
Method: We performed an overview of systematic reviews with meta-analyses of randomised controlled trials (RCTs), registered in PROSPERO (CRD42024497749). We searched Medline and Cochrane Database of Systematic Reviews.
The Brazilian Academy of Sciences commissioned a report on mental health to develop strategies for addressing mental health challenges in the post-pandemic world. These strategies should be evidence-based, culturally sensitive, resource-efficient, and promote equity, while being tailored to specific contexts. The report's proposals are meant for discussion among S20 participating Academies of Sciences, serving as a collection of ideas to influence global mental health policies, rather than mandatory guidelines.
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