Medial Gradual Opening Osteotomy of the Tibia With Monolateral External Fixator for Correcting the Varus Deformity of the Tibia.

Correction of the varus deformities in the tibia is necessary because of the excessive pressure exerted on the medial compartment of the knee, which intensifies the degenerative process. Correction strategies encompass a variety of approaches and depend on the patient's individual characteristics, age, soft tissue condition, and the orthopaedic surgeon's experience with different surgical materials. Size and location of the deformity, whether gradual or acute, play crucial roles in choosing the most appropriate material and shape.

The impact of PEEP on mechanical power and driving pressure in children with pediatric acute respiratory distress syndrome.

Background: Positive end-expiratory pressure (PEEP) is widely used to improve oxygenation and avoid alveolar collapse in mechanically ventilated patients with pediatric acute respiratory distress syndrome (PARDS). However, its improper use can be harmful, impacting variables associated with ventilation-induced lung injury, such as mechanical power (MP) and driving pressure (∆P). Our main objective was to assess the impact of increasing PEEP on MP and ∆P in children with PARDS.

The Impact of Increased PEEP on Hemodynamics, Respiratory Mechanics, and Oxygenation in Pediatric ARDS.

Background: PEEP is a cornerstone treatment for children with pediatric ARDS. Unfortunately, its titration is often performed solely by evaluating oxygen saturation, which can lead to inadequate PEEP level settings and consequent adverse effects. This study aimed to assess the impact of increasing PEEP on hemodynamics, respiratory system mechanics, and oxygenation in children with ARDS.

A new Xe irradiation system for I production.

Since 2001, Nuclear and Energy Research Institute IPEN-CNEN has produced weekly ultrapure iodine-123, using a manual irradiation system, fully developed in IPEN. Iodine-123 radiopharmaceuticals have been produced and distributed to hospitals and clinics of nuclear medicine, where several diagnostic imaging procedures for thyroid, brain and cardiovascular functions are performed. Due to the short half-life and emission of low-energy photons, this radioisotope becomes suitable for diagnosis in children.

Adrenal incidentaloma: Do patients with apparently nonfunctioning mass or autonomous cortisol secretion have similar or different clinical and metabolic features?

Objective: Although there is growing evidence associating nonfunctioning adrenal incidentalomas (NFAI) with cardiovascular risk factors, there are limited data whether NFAI and autonomous cortisol secretion (ACS) groups have similar or different clinical and metabolic features. The aim of this study is to compare cardiometabolic clinic parameters among patients with ACS and NFAI, as well as controls.

Design: Cross-sectional study.