Challenges and Policy Considerations of the Medicaid Unwinding for People with Disabilities.

Medicaid unwinding is the process of returning to normal operations after the COVID-19 Public Health Emergency's Medicaid continuous enrollment provision, which ended on March 31, 2023. This unwinding of the continuous enrollment provision may have a profound effect on Medicaid enrollees with disabilities. These enrollees may have more difficulty navigating administrative and logistical hurdles to completing redetermination, and loss of coverage may have a tremendous impact on their ability to access needed healthcare services.

Reflections on the Collaborative Story Analysis Method to Understand Qualitative Perspectives of Indigenous Syringe Services Program Clients.

Many scholars have cautioned that the use of Western research methods is problematic in studies with Indigenous communities given colonialist histories that have exploited Indigenous populations. One solution has been to utilize a Community-Based Participatory Research (CBPR) approach to enhance equity in research partnerships. Employing a CBPR approach, however, does not necessitate the inclusion of Indigenous Research Methods, an additional step that can further benefit studies with their explicit alignment with Indigenous worldviews and values.

Antiviral mechanisms and preclinical evaluation of amantadine analogs that continue to inhibit influenza A viruses with M2-based drug resistance.

To better manage seasonal and pandemic influenza infections, new drugs are needed with enhanced activity against amantadine- and rimantadine-resistant influenza A virus (IAV) strains containing the S31N variant of the viral M2 ion channel (M2). Here we tested 36 amantadine analogs against a panel of viruses containing either M2 or the parental, M2 S31 wild-type variant (M2). We found that several analogs, primarily those with sizeable lipophilic adducts, inhibited up to three M2-containing viruses with activities at least 5-fold lower than rimantadine, without inhibiting M2 proton currents or modulating endosomal pH.

Environmental water requirements and climate sensitivity of Australia's upland swamps.

In South-East Australia, headwater peatlands (or upland swamps) support ecological communities that are listed as endangered under environmental legislation. Upland swamps provide ecosystem services via water stored within their sediments, and the regulation of flows to downstream environments. However, the impacts of climate change on their hydrology remains poorly understood.