Innovations in Nipple-areolar Complex Reconstruction: Evaluation of a New Prosthesis.

Background: The reconstruction of the nipple-areola complex (NAC) is a crucial step for completing breast restoration with patient satisfaction. Surgical reconstruction or tattooing of the NAC may not be preferable or feasible for some patients. There is no universal method for NAC that is ideal for every patient or clinical situation.

Murphy's Law and Aesthetic Surgery: Are Outcomes Worse in Medical Doctor and Very Important Patients?

: Surgeons have long been aware of Murphy's Law: "If anything can go wrong, it will". When applied to surgery, Murphy's Law suggests that if there is a way that an operation can be set up incorrectly then someday, somewhere, it will be set up incorrectly. This paper focuses on complications in medical doctor (MD) and VIPs during aesthetic surgery.

Decoding the Challenges: navigating Intact Peptide Mass Spectrometry-Based Analysis for Biological Applications.

Quantitative analysis of peptides in biological fluids offers a high diagnostic and prognostic tool to reflect the pathophysiological condition of the patient. Recently, methods based on liquid chromatography coupled with mass spectrometry (LC-MS) for the quantitative determination of intact peptides have been replacing traditionally used ligand-binding assays, which suffer from cross-reactivity issues. The use of "top-down" analysis of peptides is rapidly increasing since it does not undergo incomplete or non-reproducible digestion like "bottom-up" approaches.

Custom GC×GC configuration for the selective isolation or removal of compounds from complex samples.

We developed a novel approach to selectively isolate or remove nearly any compound from complex mixtures of volatile organic compounds. This was achieved by customizing a GC×GC system with a Deans switch, a passive splitter, and a custom-made adapter for sample recollection. The new setup was evaluated with 106 standard chemicals covering a wide range of volatility (boiling points: 56 - 343 ⁰C) and polarity (log P: 0.