Association between PM2.5 and skin redness features in Taiwan.

Air pollution, particularly fine particulate matter (PM2.5), has been associated with various health issues, but its effects on skin health, specifically skin redness, remain underexplored. This study aims to examine the relationship between PM2.

The role of reservoir size in driving methane emissions in China.

Reservoirs play a crucial role as sources of methane (CH₄) emissions, with emission rates and quantities varying widely depending on reservoir size due to factors such as surface area, water depth, usage, operational methods, and spatial distribution. Gaining insights into emission characteristics across different reservoir sizes can aid in designing and managing reservoirs to mitigate CH₄ emissions effectively. In this study, machine learning models were applied to estimate both diffusive and ebullitive CH₄ emissions across 97,435 reservoirs in China, spanning five categories of storage capacity.

Estrogen-related receptor alpha (ERRα) controls the stemness and cellular energetics of prostate cancer cells via its direct regulation of citrate metabolism and zinc transportation.

Compared to most tumors that are more glycolytic, primary prostate cancer is less glycolytic but more dependent on TCA cycle coupled with OXPHOS for its energy demand. This unique metabolic energetic feature is attributed to activation of mitochondrial m-aconitase in TCA caused by decreased cellular Zn level. Evidence suggests that a small subpopulation of cancer cells within prostate tumors, designated as prostate cancer stem cells (PCSCs), play significant roles in advanced prostate cancer progression.

Depression Self-Care Apps' Characteristics and Applicability to Older Adults: Systematic Assessment.

Background: Depression affects 32% of older adults. Loneliness and social isolation are common risk factors for depression in older adults. Mobile apps can connect users and are also effective in depression management in the general population.

improves host metabolism in diet-induced obesity.

Next-generation live biotherapeutics are promising to aid the treatment of obesity and metabolic diseases. Here, we reported a novel anti-obesity probiotic candidate, , that was depleted in stool samples of obese subjects compared with lean controls, and its abundance was negatively correlated with body mass index and serum triglycerides. Supplementation of prevented body weight gain and disorders of glucose and lipid metabolism, prevented fatty liver, inhibited white adipose tissue expansion and brown adipose tissue whitening in mice fed with high-fat diet, and boosted the abundance of lean-related species.