Cancer Biother Radiopharm
January 2025
This retrospective multicenter study investigated the biodistribution of Fluorodeoxyglucose (F-FDG) in the positron emission tomography (PET)/computed tomography (CT) in digital PET/CT (dPET) compared to analog PET/CT (aPET), focusing differences in physiological uptake in reference and small structures across various scanner models. One hundred thirty patients with similar preimaging conditions underwent both dPET and aPET imaging within 6 months. Visual evaluations and paired comparative analyses of semiquantitative parameters were performed for small and reference structures.
View Article and Find Full Text PDFObjective: This study was carried out to understand whether Q.Clear and ordered subset expectation maximization (OSEM), reconstruction algorithms used in fluorine-18-fluorodeoxyglucose (F-FDG) positron emission tomography/computed tomography (PET/CT) applications, and parameters such as time of flight (TOF) and point spread function (PSF) cause different results in semi-quantitative measurements.
Subjects And Methods: Raw PET data of 264 patients who were referred to F-FDG PET/CT imaging with the purpose of evaluation of known or suspicious malignant disease were reconstructed separately with Q.
Mol Imaging Radionucl Ther
October 2023
A 61-year-old male patient, who had undergone radical prostatectomy, underwent Ga labeled prostate-specific membrane antigen (PSMA) positron emission tomography/computerized tomography (PET/CT) for evaluation of suspected biochemical recurrence of prostate cancer (PCa). PET/CT scan showed increased Ga PSMA expressions in hypodense mass lesions in both adrenal gland localizations. An adrenal gland tru-cut biopsy was performed for the right side, which showed poor-differentiated carcinoma metastases associated with the patient's high-grade PCa.
View Article and Find Full Text PDFMol Imaging Radionucl Ther
June 2022
Objectives: The present study aimed to identify the prevalence of focal uptake in the colon on fluorine-fluorodeoxyglucose (F-FDG) positron emission tomography/computed tomography (PET/CT) studies performed for the evaluation of malignancies other than colon, to detect the rate of malignancy in incidental focal F-FDG avid colonic lesions and to investigate if any possible role of maximum standardized uptake value (SUV) values in the discrimination of malignant lesions from premalignant and benign ones exist.
Methods: We retrospectively reviewed the files of 8,017 patients with known or suspected malignancy, who underwent whole-body F-FDG PET/CT at our institution during the period November 2017 to November 2019. Patients showing a single site of focally increased colonic F-FDG uptake that was more intense compared to liver uptake on F-FDG PET studies and referred to colonoscopy were enrolled in the study.
Objective: In patients with metastatic castration-resistant prostate cancer (mCRPCa), enzalutamide is administered when docetaxel treatment fails. The purpose of the study was to evaluate the relationship between prostate-specific antigen (PSA) response and metabolic parameters obtained from 68Ga-PSMA PET/CT before treatment in this patient group.
Methods: From February 2018 to May 2020, 34 patients with mCRPCa were enrolled in this study.