[Radioprotection: doctrinaire references and medical surveillance].

The current statement of radioprotection, as formulated in the 60/90 ICRP Publication and confirmed in the recent 103/07 ICRP Publication, strengths the conceptual principle of the optimization, justification and limitation of doses, it analyses the risk and proposes the values of dose limitation, according to socio-medical considerations. The medical radioprotection's aim moved from the limitation of deterministic damages ("tissue reactions" according to ICRP 103/07) to the probability's reduction of stochastic effects appearance. The "tissue reaction problem" was solved maintaining the exposition limits under the threshold.

[Medical surveillance of previously asbestos-exposed workers: report of a case of lung cancer with high level of serum mesothelin].

Recently, the number of previously asbestos-exposed workers performing, at our department, medical exams aimed at an early diagnosis of asbestos-related tumors, has been progressively increasing. The diagnostical protocol we propose to these subjects include both radiological exams and some serum markers such as mesothelin and osteopontin. In this case-report we illustrate the history of a worker who, after having diagnosed a pulmonary asbestosis, developed a Lung Cancer.

[Evaluation of a series of serum mesothelin in patients with pleural malignant mesothelioma].

Pleural Malignant Mesothelioma (MM) is a highly aggressive neoplasm with a poor survival rate, hard diagnosis and treatment. The incidence of MM in Western Europe countries is expected to increase drammatically in the next 10-15 years. In spite of this drammatic scenario, at this time the only instruments for screening and early diagnosis are based on radiological tests with evident ethical and economical problems.

[Epidemiologic surveillance in occupational bladder cancer: a Tuscan experience].

The percentage of bladder cancer as occupational disease in West-Europe is of 5/10%, but only a few amount of them are recognized as occupational disease from INAIL. The above mentioned research project is realized in order to decrease the gap between expected and claimed cases of occupational disease and it is conducted with the collaboration of ASL of Pisa, ASL of Empoli, Azienda Ospedaliera Universitaria Pisana and INAIL. 677 patients with bladder cancer were interviewed by phone, among them 64 subjects had a working experience compatible with neoplastic risks because had a previous occupational exposure to aromatic amines and metal working fluids.