Publications by authors named "F Oswald"
In a patient with permanent neonatal syndromic diabetes clinically similar to cases with ONECUT1 biallelic mutations, we identified a disease-causing deletion located upstream of ONECUT1. Through genetic, genomic, and functional studies, we identified a crucial regulatory region acting as an enhancer of ONECUT1 specifically during pancreatic development. This enhancer region contains a low-frequency variant showing a strong association with type 2 diabetes and other glycemic traits, thus extending the contribution of this region to common forms of diabetes.
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- - The study examines how different levels of registered nurse (RN) staffing in Patient Aligned Care Teams (PACTs) within the Veterans Health Administration (VHA) affect patient access to healthcare services.
- - It involved analyzing data from nearly 6,000 PACTs over a 24-month period, categorizing RN staffing stability into continuous churn, instability, vacancy, and stability, comparing their impact on various access measures.
- - Findings indicated that RN churn significantly negatively impacted appointment availability, while staffing instability and vacancy did not show a notable effect; overall, adequate staffing and team stability were linked to better patient access.
Organizations increasingly recognize the importance of including neurodivergent people (e.g., those with attention-deficit/hyperactivity disorder [ADHD], autism, dyslexia) in the workforce.
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- Measuring person-occupation fit is crucial for helping individuals, especially young people and jobseekers, find suitable majors and jobs, but current tools often focus on single areas, ignoring how fit varies across different domains.
- This research introduces an integrative set of assessments that evaluate 88 fit dimensions across five domains related to occupational success, enhancing the accuracy of career predictions.
- The findings emphasize that integrating multiple fit dimensions leads to better outcomes in career choice and success, while highlighting that certain measures, like interests and knowledge, are more impactful than others, underscoring the need for further research and practical use of these assessments.
Background: This study evaluates the psychometric properties of the newly developed semi-structured interview, Interview Version of the Symptoms and Functioning Severity Scale (SFSS-I), which is designed to provide a dimensional assessment of internalizing and externalizing symptoms.
Methods: Multi-informant baseline data from the OPTIE study was used, involving 358 children and adolescents aged 6 to 17 years (M = 11.54, SD = 3.