Publications by authors named "F Osorio"
Frequent glucose monitoring is essential for effective diabetes management. Currently, glucose monitoring is done using invasive methods such as finger-pricking and subcutaneous sensing. However, these methods can cause discomfort, heighten the risk of infection, and some sensing devices need frequent calibration.
View Article and Find Full Text PDF(1) Background: Breast cancer (BC) has a high incidence in Europe, particularly in older adults. Traditionally under-represented in clinical trials, this age group is often undertreated due to ageism. This study aims to characterize frail older adults (≥70 years) with BC based on a comprehensive geriatric assessment, to guide individualized treatment decision-making.
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- - The study explores the nonlinear optical properties of a new pyrimidine derivative, PMMS, confirmed through X-ray diffraction and geometry optimization methods.
- - Key interactions were analyzed, showing enhanced NLO behavior in PMMS, with a noteworthy improvement in third-order nonlinear susceptibility compared to known chalcone derivatives.
- - Additionally, PMMS demonstrates potential as a potent acetylcholinesterase inhibitor, suggesting its use in treating neurodegenerative diseases like Alzheimer's and underscoring its promise in both optical and pharmaceutical fields.
Article Synopsis
- The study investigates how using small datasets to select an optimal cutoff score for the Patient Health Questionnaire-9 (PHQ-9) can lead to inaccurate results.
- Researchers evaluated whether data-driven methods for cutoff selection resulted in scores that were significantly different from the true population optimal score and if these methods produced biased accuracy estimates.
- Findings showed that many small studies frequently failed to identify the correct optimal cutoff score, particularly in smaller samples, leading to an overestimation of test sensitivity.
Recently a noncentrosymmetric single crystal of a dibenzoate derivative, namely, dimethyl-4,4'-(methylenebis(azanediyl))dibenzoate, with second harmonic generation activities at 405 nm and ultrafast self-healing activity was reported by Mondal et al. in in 2023. Here, the linear and nonlinear optical properties of this notable molecular crystal were simulated using 1,611,464 atoms in the Supermolecule approach at the DFT/CAM-B3LYP/aug-cc-pVTZ level.
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