Potential of targeting signal-transducing adaptor protein-2 in cancer therapeutic applications.

Adaptor proteins play essential roles in various intracellular signaling pathways. Signal-transducing adaptor protein-2 (STAP-2) is an adaptor protein that possesses pleckstrin homology (PH) and Src homology 2 (SH2) domains, as well as a YXXQ signal transducer and activator of transcription 3 (STAT3)-binding motif in its C-terminal region. STAP-2 is also a substrate of breast tumor kinase (BRK).

Performance of imaging interpretation, intra- and inter-reader agreement for diagnosis of pelvic endometriosis: comparison between an abbreviated and full MRI protocol.

Purpose: To compare the performance of imaging interpretation, intra- and inter-reader agreement between an abbreviated (aMRI) and full (fMRI) MRI protocol for diagnosis of pelvic endometriosis.

Methods: Seventy consecutive fMRI exams performed under suspicion of pelvic endometriosis were selected. Four radiologists (Rd) (1-10 years experience) independently evaluated presence/absence of endometriosis at 9 anatomic sites (AS).

Fast calculation method with saccade suppression for a computer-generated hologram based on Fresnel zone plate limitation.

The computer-generated hologram (CGH) is an ideal 3D technology that can satisfy all the physiological factors of the human eye (such as binocular parallax, focus adjustment and convergence etc.) by simulating the recording part of traditional optical holography with a computer. CGH has a lot of advantages such as being able to be used for animation.

Dynamic visual responses of accommodation and vergence to electro-holographic images.

Electro-holography can display images without inducing fatigue and three-dimensional (3D) sickness, i.e., visual discomfort due to viewing a stereoscopic display.