Estimates of genetic parameters for chemical traits of meat quality in Japanese black cattle.

Genetic parameters for 54 carcass and chemical traits, such as general composition (moisture, crude fat and crude protein), fatty acid composition and water-soluble compounds (free amino acids, peptides, nucleotides and sugars) of 587 commercial Japanese Black cattle were assessed. Heritability estimates for carcass traits and general composition ranged between 0.19-0.

Changes in beef sensory traits as somatic-cell-cloned Japanese black steers increased in age from 20 to 30 months.

Changes in sensory traits of longissimus muscle (LM) from 20-30-month-old cattle were investigated using somatic cell clones of Japanese black steers slaughtered at 20-, 25- and 30-months-old (n=3, 4 and 4 respectively). The fat content of LM samples at 20, 25 and 30 months were 23.7, 38.

Blocking telomerase by dietary polyphenols is a major mechanism for limiting the growth of human cancer cells in vitro and in vivo.

Animal and epidemiological studies reveal that consuming food and beverages rich in polyphenols (e.g., catechins, flavones, and antocyanines) is associated with a lower incidence of cancer, and several molecular mechanisms have been proposed for explaining this effect.

In vitro and in vivo antitumor activity of the interferon inducer bropirimine.

In vivo and in vitro antitumor effects of an interferon (IFN)-alpha inducer, bropirimine (2-amino-5-bromo-6-phenyl-4(3H)-pyrimidinone), were examined in the murine tumor system. The antitumor effects were studied in Meth A cells, which were the most sensitive to bropirimine in the murine cell lines tested. The direct inhibitory activity of the drug was not reduced when Meth A cells were incubated with bropirimine and anti-IFNs, indicating that the inhibition is not due to autocrine IFN induction from tumor cells.

Antitumor activity of T cells in lymphoid organs induced by interferon in tumor-bearing mice.

Administration of human hybrid interferon-alpha A/D (IFN) for 5 consecutive days induced antitumor activity in spleen of Meth A fibrosarcoma-bearing mice 9-10 days after cessation of IFN administration. Antitumor activity assayed by the in vivo neutralization test was found in the spleen of responding mice but not in that of progressive mice. This activity was T-cell-dependent and tumor-selective.